Direct involvement of intracerebral arteries in Takayasu's arteritis

P. Molnár, K. Hegedüs

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A man aged 20 with sudden onset of headaches and rapidly evolving spastic quadriparesis died within 3 weeks. Pathologic examination revealed intensive inflammation confined mainly to the adventitia of the aorta, the internal carotids, and all the major intracranial arteries. The gross changes and the lymphocytic and plasma cell nature of the inflammatory infiltrates were typical of Takayasu's arteritis. Thrombosis of the right internal carotid artery resulted in ischemic necrosis of the ipsilateral hemisphere. Quite recent thrombus occluded the left internal carotid artery. This seems to be the first case report on histologically proven extensive direct involvement of intracranial vessels in Takayasu's disease. The differential diagnostic aspects of the case are also briefly discussed.

Original languageEnglish
Pages (from-to)83-86
Number of pages4
JournalActa neuropathologica
Volume63
Issue number1
DOIs
Publication statusPublished - Mar 1 1984

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Keywords

  • Fatal outcome
  • Intracranial arteries
  • Takayasu's arteritis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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