Direct inhibitory effect of adenosine monophosphates on Na+-K+-dependent ATPase prepared form human gastric mucosa

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Abstract

Preparations of Na+-K+-dependent ATPase were obtained from human gastric mucosa and the effects of adenosine monosphosphates (cyclic 2′,3′-adrenosine monophosphate, cyclic 3′,5t́-adenosine monophosphate and 5′-adenosine monophosphate) on its activity were measured. Direct inhibitory effects of adenosine monophosphates on transport ATPase activity were found. The adenyl cyclase and transport ATPase systems are discussed.

Original languageEnglish
Pages (from-to)207-210
Number of pages4
JournalEuropean Journal of Pharmacology
Volume9
Issue number2
DOIs
Publication statusPublished - Feb 1970

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Keywords

  • Adenosine monophosphates
  • Human gastric mucosa
  • Na-K-dependent ATPase

ASJC Scopus subject areas

  • Pharmacology

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