Direct and carbonylative vinylation of steroidal triflates in the presence of homogeneous palladium catalysts

R. Skoda-Földes, L. Kollár, Fabio Marinelli, Antonio Arcadi

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The palladium-catalyzed vinylation of several steroid 2-enyl- and 3,5-dienyl-3 triflates and estrone-3-triflate was systematically examined using vinyltributylstannane as a vinylating agent. In carbon monoxide atmosphere the insertion of a CO molecule took place and unsaturated ketones were obtained. In this way new steroid derivatives containing unsaturated side chain were produced, which can serve as starting material for further functionalization of the steroid skeleton.

Original languageEnglish
Pages (from-to)691-695
Number of pages5
JournalSteroids
Volume59
Issue number12
DOIs
Publication statusPublished - 1994

Fingerprint

Palladium
Steroids
Carbon Monoxide
Catalysts
Estrone
Ketones
Atmosphere
Skeleton
Derivatives
Molecules

Keywords

  • carbonylative vinylation
  • homogeneous catalytic vinylation
  • palladium-containing catalysts
  • triflate esters

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Molecular Biology

Cite this

Direct and carbonylative vinylation of steroidal triflates in the presence of homogeneous palladium catalysts. / Skoda-Földes, R.; Kollár, L.; Marinelli, Fabio; Arcadi, Antonio.

In: Steroids, Vol. 59, No. 12, 1994, p. 691-695.

Research output: Contribution to journalArticle

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