Dihydroisocoumarins from fungi: Isolation, structure elucidation, circular dichroism and biological activity

Karsten Krohn, Rahim Bahramsari, Ulrich Flörke, Kerstin Ludewig, Christine Kliche-Spory, Andreas Michel, Hans Jürgen Aust, Siegfried Draeger, Barbara Schulz, Sándor Antus

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

Five known and three new dihydroisocoumarins were isolated from different fungi. The new isocoumarins are 5-chloro-6-hydroxymellein, 5- chloro-4,6-dihydroxymellein and 5,6-dihydroxymellein. The absolute configuration of these secondary metabolites was confirmed by CD measurements and in two cases by X-ray structure analysis.

Original languageEnglish
Pages (from-to)313-320
Number of pages8
JournalPhytochemistry
Volume45
Issue number2
DOIs
Publication statusPublished - May 1 1997

Keywords

  • Baker's yeast
  • Cryptosporiopsis
  • Pezicula livida
  • Plectophomella
  • X-ray
  • absolute configuration
  • circular dichroism
  • fungal metabolites
  • mel- leins

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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    Krohn, K., Bahramsari, R., Flörke, U., Ludewig, K., Kliche-Spory, C., Michel, A., Aust, H. J., Draeger, S., Schulz, B., & Antus, S. (1997). Dihydroisocoumarins from fungi: Isolation, structure elucidation, circular dichroism and biological activity. Phytochemistry, 45(2), 313-320. https://doi.org/10.1016/S0031-9422(96)00854-0