Differential scanning calorimetric examination of transverse carpal ligament in carpal tunnel disease

N. Wiegand, L. Vámhidy, B. Patczai, E. Dömse, P. Than, L. Kereskai, D. Lőrinczy

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The carpal tunnel syndrome - compression of the median nerve by the transverse ligament of the wrist - is a serious disease of the human hand. The electrophysiological changes in the median nerve can be easily followed by electroneurography (ENG). The degenerative changes in the collagen structures of the carpal ligament cause shrinking of the ligament and compression of the nerve. According to the present study we could demonstrate that DSC is a useful and well applicable method for the investigation of collagen tissue of the human carpal transverse ligament. DSC scans clearly demonstrated significant differences between the different types and conditions of samples (control: T m=61.3°C and ΔH cal=4.04 J g -1, mild: T m=62°C and ΔH cal=4.3 J g -1, middle: T m=61.5°C and ΔH cal=5.17 J g -1 as well as severe: T m=61.85°C and ΔH cal=8.44 J g -1). After these investigations we can choose the optimal time of surgical therapy of different clinical level carpal tunnel syndrome too.

Original languageEnglish
Pages (from-to)793-796
Number of pages4
JournalJournal of Thermal Analysis and Calorimetry
Volume95
Issue number3
DOIs
Publication statusPublished - Mar 2009

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ligaments
Ligaments
tunnels
Tunnels
nerves
examination
Scanning
scanning
collagens
Collagen
wrist
therapy
Tissue
causes

Keywords

  • Carpal tunnel syndrome
  • DSC
  • ENG

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Condensed Matter Physics

Cite this

Differential scanning calorimetric examination of transverse carpal ligament in carpal tunnel disease. / Wiegand, N.; Vámhidy, L.; Patczai, B.; Dömse, E.; Than, P.; Kereskai, L.; Lőrinczy, D.

In: Journal of Thermal Analysis and Calorimetry, Vol. 95, No. 3, 03.2009, p. 793-796.

Research output: Contribution to journalArticle

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