Differential sacnning calorimetric examination of the human intervertebral disc: Establishment of calorimetric standards of different stages of degeneration

I. Domán, T. Illésa, D. Lőrinczy

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Intervertebral disc (IVD) degeneration is a common orthopaedic disorder with significant social and economic impact. The major pathological changes occur in the structure of anulus fibrosus (AF) and nucleus pulposus (NP). According to previous reports differential sacnning calorimetric (DSC) proved to be a suitable method for the demonstration of thermal consequences of local and global conformational changes in the structure of the human intervertebral discs. According to the present study, the DSC results clearly proved that definitive differences are present between the stages of disc degeneration in calorimetric measures. The structural differences between the stages could be also demonstrated by histology.

Original languageEnglish
Pages (from-to)293-299
Number of pages7
JournalThermochimica Acta
Volume405
Issue number2
DOIs
Publication statusPublished - Nov 6 2003

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intervertebral disks
Histology
degeneration
Orthopedics
Demonstrations
examination
economic impact
orthopedics
Economics
histology
disorders
nuclei
Hot Temperature

Keywords

  • Anulus fibrosus
  • Degeneration
  • DSC
  • Intervertebral disc
  • Nucleus pulposus

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

Cite this

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abstract = "Intervertebral disc (IVD) degeneration is a common orthopaedic disorder with significant social and economic impact. The major pathological changes occur in the structure of anulus fibrosus (AF) and nucleus pulposus (NP). According to previous reports differential sacnning calorimetric (DSC) proved to be a suitable method for the demonstration of thermal consequences of local and global conformational changes in the structure of the human intervertebral discs. According to the present study, the DSC results clearly proved that definitive differences are present between the stages of disc degeneration in calorimetric measures. The structural differences between the stages could be also demonstrated by histology.",
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AU - Lőrinczy, D.

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AB - Intervertebral disc (IVD) degeneration is a common orthopaedic disorder with significant social and economic impact. The major pathological changes occur in the structure of anulus fibrosus (AF) and nucleus pulposus (NP). According to previous reports differential sacnning calorimetric (DSC) proved to be a suitable method for the demonstration of thermal consequences of local and global conformational changes in the structure of the human intervertebral discs. According to the present study, the DSC results clearly proved that definitive differences are present between the stages of disc degeneration in calorimetric measures. The structural differences between the stages could be also demonstrated by histology.

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