Different 57Fe microenvironments in the nanosized iron cores in human liver ferritin and its pharmaceutical analogues on the basis of temperature dependent Mössbauer spectroscopy

M. I. Oshtrakh, I. V. Alenkina, Z. Klencsár, E. Kuzmann, V. A. Semionkin

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Mössbauer spectra of human liver ferritin and its pharmaceutical analogues Ferrum Lek and Maltofer® measured at various temperatures within the range of 295-83K were fitted using five quadrupole doublets related to different 57Fe microenvironments in various layers/regions of the ferrihydrite and akaganéite iron cores. The observed anomalous temperature dependences of some Mössbauer parameters were considered as a result of low temperature structural rearrangements in different layers/regions in the iron core.

Original languageEnglish
JournalSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
DOIs
Publication statusAccepted/In press - Oct 13 2015

Fingerprint

Ferritins
liver
Liver
Drug products
Iron
Spectroscopy
analogs
iron
Pharmaceutical Preparations
spectroscopy
quadrupoles
Temperature
temperature dependence
temperature

Keywords

  • Ferrum Lek
  • Human liver ferritin
  • Iron core structure
  • Maltofer®
  • Mössbauer spectroscopy

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics
  • Analytical Chemistry
  • Spectroscopy

Cite this

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abstract = "M{\"o}ssbauer spectra of human liver ferritin and its pharmaceutical analogues Ferrum Lek and Maltofer{\circledR} measured at various temperatures within the range of 295-83K were fitted using five quadrupole doublets related to different 57Fe microenvironments in various layers/regions of the ferrihydrite and akagan{\'e}ite iron cores. The observed anomalous temperature dependences of some M{\"o}ssbauer parameters were considered as a result of low temperature structural rearrangements in different layers/regions in the iron core.",
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T1 - Different 57Fe microenvironments in the nanosized iron cores in human liver ferritin and its pharmaceutical analogues on the basis of temperature dependent Mössbauer spectroscopy

AU - Oshtrakh, M. I.

AU - Alenkina, I. V.

AU - Klencsár, Z.

AU - Kuzmann, E.

AU - Semionkin, V. A.

PY - 2015/10/13

Y1 - 2015/10/13

N2 - Mössbauer spectra of human liver ferritin and its pharmaceutical analogues Ferrum Lek and Maltofer® measured at various temperatures within the range of 295-83K were fitted using five quadrupole doublets related to different 57Fe microenvironments in various layers/regions of the ferrihydrite and akaganéite iron cores. The observed anomalous temperature dependences of some Mössbauer parameters were considered as a result of low temperature structural rearrangements in different layers/regions in the iron core.

AB - Mössbauer spectra of human liver ferritin and its pharmaceutical analogues Ferrum Lek and Maltofer® measured at various temperatures within the range of 295-83K were fitted using five quadrupole doublets related to different 57Fe microenvironments in various layers/regions of the ferrihydrite and akaganéite iron cores. The observed anomalous temperature dependences of some Mössbauer parameters were considered as a result of low temperature structural rearrangements in different layers/regions in the iron core.

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KW - Human liver ferritin

KW - Iron core structure

KW - Maltofer®

KW - Mössbauer spectroscopy

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