Different cholesterol fractions, LCAT activity and lipid peroxides in the serum of children whose parents had early coronary heart disease

Tamás Szamosi, Gábor Hacsek, Anna Szamosi, Ildikó Popovits, I. Venekei, András Jávor

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Children whose parents had early coronary heart disease were investigated for lipid abnormalities. In order to assess high risk parameters and the efficacy of the applied care, serum total cholesterol (TC), total triglyceride (TT), total free cholesterol (FC) high density lipoprotein cholesterol (HDLC), high density lipoprotein free cholesterol (HDLFC), lipid peroxide (LP) levels, and lecithin: cholesterol acyl transferase (LCAT) activity were measured. Compared to a group of control children, the offspring of high risk subjects had increased TC, FC, and LP levels and decreased HDLC levels. After one year of preventative care all parameters normalized except the high FC level and elevated LCAT activity. The measurement of serum FC and LP levels seems to be a useful method for the determination of true high risk. The LCAT activity may show the efficacy of the dietary treatment.

Original languageEnglish
Pages (from-to)97-99
Number of pages3
JournalClinical Biochemistry
Volume21
Issue number2
DOIs
Publication statusPublished - 1988

Fingerprint

Lecithins
Lipid Peroxides
Transferases
Coronary Disease
Parents
Cholesterol
Serum
HDL Cholesterol
Hypercholesterolemia
Preventive Medicine
HDL Lipoproteins
Triglycerides
Lipids
Control Groups

Keywords

  • atherosclerosis risk factors
  • cholesterol
  • LCAT activity
  • lipid peroxides
  • serum lipids

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Different cholesterol fractions, LCAT activity and lipid peroxides in the serum of children whose parents had early coronary heart disease. / Szamosi, Tamás; Hacsek, Gábor; Szamosi, Anna; Popovits, Ildikó; Venekei, I.; Jávor, András.

In: Clinical Biochemistry, Vol. 21, No. 2, 1988, p. 97-99.

Research output: Contribution to journalArticle

Szamosi, Tamás ; Hacsek, Gábor ; Szamosi, Anna ; Popovits, Ildikó ; Venekei, I. ; Jávor, András. / Different cholesterol fractions, LCAT activity and lipid peroxides in the serum of children whose parents had early coronary heart disease. In: Clinical Biochemistry. 1988 ; Vol. 21, No. 2. pp. 97-99.
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