Differences in circulating carnitine status of preterm infants fed fortified human milk or preterm infant formula

J. Bene, K. Komlósi, B. Melegh, T. Decsi, Berthold Koletzko, Ulrike Sauerwald

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

OBJECTIVE:: The aim of the study was to compare plasma carnitine profiles in fortified human milk (HM)-fed preterm infants or formula-fed preterm infants. METHODS:: Plasma acylcarnitine concentrations were determined in 20 formula-fed and 18 HM-fed preterm infants (birth weights between 1000 and 2200 g) by isotope dilution ESI MS/MS technique on study days 0, 14, and 28. RESULTS:: Concentrations of free carnitine (FC) and different acylcarnitines did not change during the 4 weeks of the study in infants fed HM. In contrast, in infants fed formula FC increased markedly (day 0: 29.989 [16.646] μmol/L, median [interquartile range], day 14: 43.972 [8.455], P

Original languageEnglish
Pages (from-to)673-676
Number of pages4
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume57
Issue number5
DOIs
Publication statusPublished - Nov 2013

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Infant Formula
Carnitine
Human Milk
Premature Infants
Premature Birth
Birth Weight
Isotopes
acylcarnitine

Keywords

  • carnitine ester profile
  • human milk
  • mass spectrometry
  • premature infant
  • preterm infant formula

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health

Cite this

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abstract = "OBJECTIVE:: The aim of the study was to compare plasma carnitine profiles in fortified human milk (HM)-fed preterm infants or formula-fed preterm infants. METHODS:: Plasma acylcarnitine concentrations were determined in 20 formula-fed and 18 HM-fed preterm infants (birth weights between 1000 and 2200 g) by isotope dilution ESI MS/MS technique on study days 0, 14, and 28. RESULTS:: Concentrations of free carnitine (FC) and different acylcarnitines did not change during the 4 weeks of the study in infants fed HM. In contrast, in infants fed formula FC increased markedly (day 0: 29.989 [16.646] μmol/L, median [interquartile range], day 14: 43.972 [8.455], P",
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author = "J. Bene and K. Koml{\'o}si and B. Melegh and T. Decsi and Berthold Koletzko and Ulrike Sauerwald",
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T1 - Differences in circulating carnitine status of preterm infants fed fortified human milk or preterm infant formula

AU - Bene, J.

AU - Komlósi, K.

AU - Melegh, B.

AU - Decsi, T.

AU - Koletzko, Berthold

AU - Sauerwald, Ulrike

PY - 2013/11

Y1 - 2013/11

N2 - OBJECTIVE:: The aim of the study was to compare plasma carnitine profiles in fortified human milk (HM)-fed preterm infants or formula-fed preterm infants. METHODS:: Plasma acylcarnitine concentrations were determined in 20 formula-fed and 18 HM-fed preterm infants (birth weights between 1000 and 2200 g) by isotope dilution ESI MS/MS technique on study days 0, 14, and 28. RESULTS:: Concentrations of free carnitine (FC) and different acylcarnitines did not change during the 4 weeks of the study in infants fed HM. In contrast, in infants fed formula FC increased markedly (day 0: 29.989 [16.646] μmol/L, median [interquartile range], day 14: 43.972 [8.455], P

AB - OBJECTIVE:: The aim of the study was to compare plasma carnitine profiles in fortified human milk (HM)-fed preterm infants or formula-fed preterm infants. METHODS:: Plasma acylcarnitine concentrations were determined in 20 formula-fed and 18 HM-fed preterm infants (birth weights between 1000 and 2200 g) by isotope dilution ESI MS/MS technique on study days 0, 14, and 28. RESULTS:: Concentrations of free carnitine (FC) and different acylcarnitines did not change during the 4 weeks of the study in infants fed HM. In contrast, in infants fed formula FC increased markedly (day 0: 29.989 [16.646] μmol/L, median [interquartile range], day 14: 43.972 [8.455], P

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KW - preterm infant formula

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