Liver tissue of phylogenetically different animals was transplanted into the anterior chamber of albino rats' eyes. In autotransplantation only the biliary ducts remained alive and regeneration started from these; transplants from homologous and heterologous mammals and fowls were destroyed, transplants from fish and triturus remained alive. Transplanted liver tissue cultivated on rat serum showed that all the tissues which remained alive in vitro, survived also in vivo. In accordance with previous experiments, it is concluded that mainly those tissues remain alive as transplantats, which are able to assimilate foreign proteins in vivo and in vitro. In the behaviour of heterotransplants three phases can be distinguished: 1. The phase of traumatisation and local disturbances in nutrition. 2. The phase of assimilation and adaptation. 3. The phase of immune reaction. It is the second phase which is of the greatest importance for the fate of the transplant.
ASJC Scopus subject areas
- Pathology and Forensic Medicine