Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Ralph W. Adams, Liam Byrne, Péter Király, Mohammadali Foroozandeh, Liladhar Paudel, Mathias Nilsson, Jonathan Clayden, Gareth A. Morris

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54 Citations (Scopus)

Abstract

An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.

Original languageEnglish
Pages (from-to)2512-2514
Number of pages3
JournalChemical Communications
Volume50
Issue number19
DOIs
Publication statusPublished - Mar 7 2014

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ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Adams, R. W., Byrne, L., Király, P., Foroozandeh, M., Paudel, L., Nilsson, M., Clayden, J., & Morris, G. A. (2014). Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy. Chemical Communications, 50(19), 2512-2514. https://doi.org/10.1039/c3cc49659g