Diagnostic value of the left atrial electrical potentials detected by body surface potential mapping in the prediction of coronary artery disease

Tamás Bauernfeind, I. Préda, Krisztina Szakolczai, Endre Szucs, R. Kiss, Gábor Simonyi, Gábor Kerecsen, G. Duray, Mihály Medvegy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: The electrocardiographic diagnosis of significant coronary artery stenosis (CAD) is often based on the investigation of the left ventricular repolarization changes during exercise ECG stress test (EST). Our aim was to prove that the electric activity of the left atrium can indicate the ischemic damage of the left ventricle, and furthermore, it is able to indicate CAD without exercise. Methods and results: Patients with chest complaints but without evidence of acute coronary syndrome were investigated by EST and body surface potential mapping (BSPM, 63 leads). CAD was proven in 45 cases (32 men, years 40-76) and excluded in 50 cases (35 men, years 38-72) with coronary angiography. Left atrial electric potentials (EP-LA) before and after 0.08 mg sublingual nitroglycerine administration differed significantly (p <0.001) in the two groups. According to Fischer linear discriminant analysis, this difference in % (EP-LA d%) was the best separating parameter: below limit of -14.17% (CAD prevalence was considered) this parameter predicted CAD with 93% sensitivity, 100% specificity, > 10 positive and 0.05 negative likelihood ratio (weighted for prevalence). The EST predicted CAD with 71% sensitivity, 78% specificity, 2.43 positive and 0.28 negative likelihood ratios. Conclusion: The electrical activity changes of the left atrium seemed to be suitable to predict CAD as an EST-alternative resting method.

Original languageEnglish
Pages (from-to)315-318
Number of pages4
JournalInternational Journal of Cardiology
Volume150
Issue number3
DOIs
Publication statusPublished - Aug 4 2011

Fingerprint

Body Surface Potential Mapping
Exercise Test
Coronary Artery Disease
Electrocardiography
Heart Atria
Sublingual Administration
Exercise
Coronary Stenosis
Nitroglycerin
Acute Coronary Syndrome
Coronary Angiography
Heart Ventricles
Thorax
Sensitivity and Specificity

Keywords

  • Body surface potential mapping
  • Coronary artery disease
  • Exercise ECG test
  • Left atrium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Diagnostic value of the left atrial electrical potentials detected by body surface potential mapping in the prediction of coronary artery disease. / Bauernfeind, Tamás; Préda, I.; Szakolczai, Krisztina; Szucs, Endre; Kiss, R.; Simonyi, Gábor; Kerecsen, Gábor; Duray, G.; Medvegy, Mihály.

In: International Journal of Cardiology, Vol. 150, No. 3, 04.08.2011, p. 315-318.

Research output: Contribution to journalArticle

Bauernfeind, Tamás ; Préda, I. ; Szakolczai, Krisztina ; Szucs, Endre ; Kiss, R. ; Simonyi, Gábor ; Kerecsen, Gábor ; Duray, G. ; Medvegy, Mihály. / Diagnostic value of the left atrial electrical potentials detected by body surface potential mapping in the prediction of coronary artery disease. In: International Journal of Cardiology. 2011 ; Vol. 150, No. 3. pp. 315-318.
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