A szérum alpha 2-HS-glycoprotein meghatározások diagnosztikus értékéröl.

Translated title of the contribution: Diagnostic value of the determination of serum alpha2-HS-glycoprotein

L. Kalabay, K. Cseh, L. Jakab, T. Pozsonyi, L. Jakab, S. Benedek, S. Fekete, L. Telegdy

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Opsonic glycoprotein, alpha 2-HS-glycoprotein concentration was studied in the serum of 753 patients with various hematological, malignant, immunological, metabolic, endocrine and liver diseases and 68 healthy controls. Decreased serum alpha 2-HS-glycoprotein levels were detected in patients with acute leukemias, chronic granulocyte and myelomonocyte leukemias, lymphomas, myelofibrosis, multiple myeloma, metastatizing solid tumors, systemic lupus erythematosus, rheumatoid arthritis, acute alcoholic hepatitis, fatty liver, chronic active hepatitis, liver cirrhosis, acute and chronic pancreatitis, and Crohn's disease. Elevated levels were measured in patients with B and NANB/C hepatitis. Further decreased levels were observed in some groups with secondary infections. Serum alpha 2-HS-glycoprotein levels are affected by many factors, influencing the synthesis and elimination of the protein. The detection of serum alpha 2-HS-glycoprotein concentration has no specific diagnostic value as a marker for tumors or other diseases, however, its determination can be useful for the assessment of a non-specific regulator of the host defence.

Original languageHungarian
Pages (from-to)1553-1554; 1559-1560
JournalOrvosi hetilap
Volume133
Issue number25
Publication statusPublished - Jun 21 1992

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kalabay, L., Cseh, K., Jakab, L., Pozsonyi, T., Jakab, L., Benedek, S., Fekete, S., & Telegdy, L. (1992). A szérum alpha 2-HS-glycoprotein meghatározások diagnosztikus értékéröl. Orvosi hetilap, 133(25), 1553-1554; 1559-1560.