Abstract
The diagnostic value of the estimation of faecal elastase-1, the new noninvasive direct pancreatic function test was evaluated in a total of 35 patients. Twenty one patients were diagnosed with chronic pancreatitis and categorized according to grades of exocrine pancreatic insufficiency based on the Lundh test, 14 patients in the control group had gastrointestinal disorders. Faecal elastase 1 was measured by ELISA method. The sensitivity, specificity, positive and negative predictive value and diagnostic accuracy of elastase determination was 71.4%, 92.8%, 88.2%, 81.2% and 83.7%, respectively in chronic pancreatitis. In the severe exocrine pancreas insufficiency group (n = 14), the sensitivity was 85.7%, while in the group with mild insufficiency (n = 7) the sensitivity was only 42.8%. The determination of faecal elastase is useful in the diagnosis of severe exocrine pancreas insufficiency, but it is not sensitive enough in the mild form of the disease.
| Original language | Hungarian |
|---|---|
| Pages (from-to) | 1887-1890 |
| Number of pages | 4 |
| Journal | Orvosi Hetilap |
| Volume | 140 |
| Issue number | 34 |
| Publication status | Published - Aug 22 1999 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
A széklet elasztáz-teszt diagnosztikus értéke exokrin pancreas-elégtelenségben. / Czakó, L.; Takács, T.; Farkas, G.; Boda, K.; Lonovics, J.
In: Orvosi Hetilap, Vol. 140, No. 34, 22.08.1999, p. 1887-1890.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A széklet elasztáz-teszt diagnosztikus értéke exokrin pancreas-elégtelenségben.
AU - Czakó, L.
AU - Takács, T.
AU - Farkas, G.
AU - Boda, K.
AU - Lonovics, J.
PY - 1999/8/22
Y1 - 1999/8/22
N2 - The diagnostic value of the estimation of faecal elastase-1, the new noninvasive direct pancreatic function test was evaluated in a total of 35 patients. Twenty one patients were diagnosed with chronic pancreatitis and categorized according to grades of exocrine pancreatic insufficiency based on the Lundh test, 14 patients in the control group had gastrointestinal disorders. Faecal elastase 1 was measured by ELISA method. The sensitivity, specificity, positive and negative predictive value and diagnostic accuracy of elastase determination was 71.4%, 92.8%, 88.2%, 81.2% and 83.7%, respectively in chronic pancreatitis. In the severe exocrine pancreas insufficiency group (n = 14), the sensitivity was 85.7%, while in the group with mild insufficiency (n = 7) the sensitivity was only 42.8%. The determination of faecal elastase is useful in the diagnosis of severe exocrine pancreas insufficiency, but it is not sensitive enough in the mild form of the disease.
AB - The diagnostic value of the estimation of faecal elastase-1, the new noninvasive direct pancreatic function test was evaluated in a total of 35 patients. Twenty one patients were diagnosed with chronic pancreatitis and categorized according to grades of exocrine pancreatic insufficiency based on the Lundh test, 14 patients in the control group had gastrointestinal disorders. Faecal elastase 1 was measured by ELISA method. The sensitivity, specificity, positive and negative predictive value and diagnostic accuracy of elastase determination was 71.4%, 92.8%, 88.2%, 81.2% and 83.7%, respectively in chronic pancreatitis. In the severe exocrine pancreas insufficiency group (n = 14), the sensitivity was 85.7%, while in the group with mild insufficiency (n = 7) the sensitivity was only 42.8%. The determination of faecal elastase is useful in the diagnosis of severe exocrine pancreas insufficiency, but it is not sensitive enough in the mild form of the disease.
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M3 - Article
C2 - 10502971
AN - SCOPUS:0033595320
VL - 140
SP - 1887
EP - 1890
JO - Orvosi Hetilap
JF - Orvosi Hetilap
SN - 0030-6002
IS - 34
ER -