Diagnostic value of contrast-enhanced ultrasound and contrast-enhanced CT for renal solid space-occupying lesions

A meta-analysis

Bang Tao Chen, Jun Jie Chi, Shi Jie Hou, Yun Zhang, Shao Juan Song, Ming She Liu, Z. Zhao

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective To systematically review the differential diagnostic value of contrast-enhanced ultrasound (CEUS) and contrast-enhanced CT (CECT) for renal solid space-occupying lesions. Methods Databases including EMbase, PubMed, The Cochrane Library (Issue 11, 2014), CNKI, CBM, VIP and WanFang Data were searched for diagnostic tests about CEUS and CECT for renal solid space-occupying lesions from inception to September, 2014. Two reviewers independently screened literature, extracted data and assessed the methodological quality of included studies. Then meta-analysis was performed using Meta-Disc 1.4 software. Results A total of 13 studies involving 754 specimens were included. The results of meta-analysis showed that: the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio (combined effect and its 95%CI) in the CEUS group were 0.96 (95%CI 0.94 to 0.97), 0.77 (95%CI 0.70 to 0.83), 3.82 (95%CI 2.93 to 4.97), 0.06 (95%CI 0.04 to 0.10), 64.33 (95%CI 36.79 to 112.51), and in the CECT group were 0.84 (95%CI 0.81 to 0.87), 0.73 (95%CI 0.65 to 0.79), 2.81 (95%CI 2.22 to 3.56), 0.23 (95%CI 0.16 to 0.34), 13.85 (95%CI 6.79 to 28.26). There were significant differences between the CEUS group (0.960 8, 95%CI 0.927 3 to 0.994 3) and the CECT group (0.866 8, 95%CI 0.788 8 to 0.944 8) in the area under the summary receiver operating characteristic (SROC) curve (P

Original languageEnglish
Pages (from-to)1042-1048
Number of pages7
JournalChinese Journal of Evidence-Based Medicine
Volume15
Issue number9
DOIs
Publication statusPublished - 2015

Fingerprint

Meta-Analysis
Kidney
Routine Diagnostic Tests
PubMed
ROC Curve
Libraries
Software
Odds Ratio
Databases
Sensitivity and Specificity

Keywords

  • Contrast-enhanced CT
  • Contrast-enhanced ultrasound
  • Diagnostic test
  • Metaanalysis
  • Renal
  • Renal solid space-occupying

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diagnostic value of contrast-enhanced ultrasound and contrast-enhanced CT for renal solid space-occupying lesions : A meta-analysis. / Chen, Bang Tao; Chi, Jun Jie; Hou, Shi Jie; Zhang, Yun; Song, Shao Juan; Liu, Ming She; Zhao, Z.

In: Chinese Journal of Evidence-Based Medicine, Vol. 15, No. 9, 2015, p. 1042-1048.

Research output: Contribution to journalArticle

Chen, Bang Tao ; Chi, Jun Jie ; Hou, Shi Jie ; Zhang, Yun ; Song, Shao Juan ; Liu, Ming She ; Zhao, Z. / Diagnostic value of contrast-enhanced ultrasound and contrast-enhanced CT for renal solid space-occupying lesions : A meta-analysis. In: Chinese Journal of Evidence-Based Medicine. 2015 ; Vol. 15, No. 9. pp. 1042-1048.
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abstract = "Objective To systematically review the differential diagnostic value of contrast-enhanced ultrasound (CEUS) and contrast-enhanced CT (CECT) for renal solid space-occupying lesions. Methods Databases including EMbase, PubMed, The Cochrane Library (Issue 11, 2014), CNKI, CBM, VIP and WanFang Data were searched for diagnostic tests about CEUS and CECT for renal solid space-occupying lesions from inception to September, 2014. Two reviewers independently screened literature, extracted data and assessed the methodological quality of included studies. Then meta-analysis was performed using Meta-Disc 1.4 software. Results A total of 13 studies involving 754 specimens were included. The results of meta-analysis showed that: the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio (combined effect and its 95{\%}CI) in the CEUS group were 0.96 (95{\%}CI 0.94 to 0.97), 0.77 (95{\%}CI 0.70 to 0.83), 3.82 (95{\%}CI 2.93 to 4.97), 0.06 (95{\%}CI 0.04 to 0.10), 64.33 (95{\%}CI 36.79 to 112.51), and in the CECT group were 0.84 (95{\%}CI 0.81 to 0.87), 0.73 (95{\%}CI 0.65 to 0.79), 2.81 (95{\%}CI 2.22 to 3.56), 0.23 (95{\%}CI 0.16 to 0.34), 13.85 (95{\%}CI 6.79 to 28.26). There were significant differences between the CEUS group (0.960 8, 95{\%}CI 0.927 3 to 0.994 3) and the CECT group (0.866 8, 95{\%}CI 0.788 8 to 0.944 8) in the area under the summary receiver operating characteristic (SROC) curve (P",
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T1 - Diagnostic value of contrast-enhanced ultrasound and contrast-enhanced CT for renal solid space-occupying lesions

T2 - A meta-analysis

AU - Chen, Bang Tao

AU - Chi, Jun Jie

AU - Hou, Shi Jie

AU - Zhang, Yun

AU - Song, Shao Juan

AU - Liu, Ming She

AU - Zhao, Z.

PY - 2015

Y1 - 2015

N2 - Objective To systematically review the differential diagnostic value of contrast-enhanced ultrasound (CEUS) and contrast-enhanced CT (CECT) for renal solid space-occupying lesions. Methods Databases including EMbase, PubMed, The Cochrane Library (Issue 11, 2014), CNKI, CBM, VIP and WanFang Data were searched for diagnostic tests about CEUS and CECT for renal solid space-occupying lesions from inception to September, 2014. Two reviewers independently screened literature, extracted data and assessed the methodological quality of included studies. Then meta-analysis was performed using Meta-Disc 1.4 software. Results A total of 13 studies involving 754 specimens were included. The results of meta-analysis showed that: the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio (combined effect and its 95%CI) in the CEUS group were 0.96 (95%CI 0.94 to 0.97), 0.77 (95%CI 0.70 to 0.83), 3.82 (95%CI 2.93 to 4.97), 0.06 (95%CI 0.04 to 0.10), 64.33 (95%CI 36.79 to 112.51), and in the CECT group were 0.84 (95%CI 0.81 to 0.87), 0.73 (95%CI 0.65 to 0.79), 2.81 (95%CI 2.22 to 3.56), 0.23 (95%CI 0.16 to 0.34), 13.85 (95%CI 6.79 to 28.26). There were significant differences between the CEUS group (0.960 8, 95%CI 0.927 3 to 0.994 3) and the CECT group (0.866 8, 95%CI 0.788 8 to 0.944 8) in the area under the summary receiver operating characteristic (SROC) curve (P

AB - Objective To systematically review the differential diagnostic value of contrast-enhanced ultrasound (CEUS) and contrast-enhanced CT (CECT) for renal solid space-occupying lesions. Methods Databases including EMbase, PubMed, The Cochrane Library (Issue 11, 2014), CNKI, CBM, VIP and WanFang Data were searched for diagnostic tests about CEUS and CECT for renal solid space-occupying lesions from inception to September, 2014. Two reviewers independently screened literature, extracted data and assessed the methodological quality of included studies. Then meta-analysis was performed using Meta-Disc 1.4 software. Results A total of 13 studies involving 754 specimens were included. The results of meta-analysis showed that: the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio (combined effect and its 95%CI) in the CEUS group were 0.96 (95%CI 0.94 to 0.97), 0.77 (95%CI 0.70 to 0.83), 3.82 (95%CI 2.93 to 4.97), 0.06 (95%CI 0.04 to 0.10), 64.33 (95%CI 36.79 to 112.51), and in the CECT group were 0.84 (95%CI 0.81 to 0.87), 0.73 (95%CI 0.65 to 0.79), 2.81 (95%CI 2.22 to 3.56), 0.23 (95%CI 0.16 to 0.34), 13.85 (95%CI 6.79 to 28.26). There were significant differences between the CEUS group (0.960 8, 95%CI 0.927 3 to 0.994 3) and the CECT group (0.866 8, 95%CI 0.788 8 to 0.944 8) in the area under the summary receiver operating characteristic (SROC) curve (P

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KW - Metaanalysis

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