Diagnosztikai nehézséget okozó pulmonalis infiltrátum

Translated title of the contribution: Diagnostic diffi culties caused by a pulmonary infi ltrate

Zsófia Simon, Ádám Jóna, Zsófia Miltényi, Edit Páyer, Attila Lieber, Mária Szilasi, A. Illés

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Lung infiltration still causes differential diagnostic difficulties, which may delay the start of definitive treatment. Case report: The examination of a 30-year-old man began due intermittent, remittent and permanent fever. Chest X-ray confirmed infiltration in the right upper lobe, which was accompanied by elevated CRP and physiological levels of procalcitonin. Most likely atypical pneumonia, tuberculosis, Wegener's granulomatosis or a malignant process was suspected. Throughout his examination infection could not be verified, repeated CT guided transthoracic needle biopsy suggested the possibility of a malignant process. Through surgical exploration the intraoperative histology was not informative; thus, the pneumonitis-remodelled right lung was removed due to the possibility of malignant transformation. Histological examination revealed lymphocyte rich classical Hodgkin lymphoma, which was found to be stage IV/B based on the 18FDG-PET/CT scan; therefore, eight cycles of ABVD (adriablastin, bleomycin, vinblastine, and dacarbazine) therapy was administered successfully. The patient is currently (for 30 months) in a complete metabolic remission. Conclusion: Primary pulmonary Hodgkin lymphoma is a rare disease entity (in this case it might be the original process), in which the diagnosis is often difficult. 18FDG-PET/CT may be a useful early diagnostic tool investigating fever of unknown origin.

Original languageHungarian
Pages (from-to)1077-1081
Number of pages5
JournalOrvosi Hetilap
Volume153
Issue number27
DOIs
Publication statusPublished - Jul 1 2012

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Fluorodeoxyglucose F18
Hodgkin Disease
Lung
Pneumonia
Fever of Unknown Origin
Dacarbazine
Granulomatosis with Polyangiitis
Vinblastine
Bleomycin
Calcitonin
Needle Biopsy
Rare Diseases
Doxorubicin
Malaria
Histology
Tuberculosis
Thorax
X-Rays
Therapeutics
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Simon, Z., Jóna, Á., Miltényi, Z., Páyer, E., Lieber, A., Szilasi, M., & Illés, A. (2012). Diagnosztikai nehézséget okozó pulmonalis infiltrátum. Orvosi Hetilap, 153(27), 1077-1081. https://doi.org/10.1556/OH.2012.29404

Diagnosztikai nehézséget okozó pulmonalis infiltrátum. / Simon, Zsófia; Jóna, Ádám; Miltényi, Zsófia; Páyer, Edit; Lieber, Attila; Szilasi, Mária; Illés, A.

In: Orvosi Hetilap, Vol. 153, No. 27, 01.07.2012, p. 1077-1081.

Research output: Contribution to journalArticle

Simon, Z, Jóna, Á, Miltényi, Z, Páyer, E, Lieber, A, Szilasi, M & Illés, A 2012, 'Diagnosztikai nehézséget okozó pulmonalis infiltrátum', Orvosi Hetilap, vol. 153, no. 27, pp. 1077-1081. https://doi.org/10.1556/OH.2012.29404
Simon Z, Jóna Á, Miltényi Z, Páyer E, Lieber A, Szilasi M et al. Diagnosztikai nehézséget okozó pulmonalis infiltrátum. Orvosi Hetilap. 2012 Jul 1;153(27):1077-1081. https://doi.org/10.1556/OH.2012.29404
Simon, Zsófia ; Jóna, Ádám ; Miltényi, Zsófia ; Páyer, Edit ; Lieber, Attila ; Szilasi, Mária ; Illés, A. / Diagnosztikai nehézséget okozó pulmonalis infiltrátum. In: Orvosi Hetilap. 2012 ; Vol. 153, No. 27. pp. 1077-1081.
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