Juhok Eperythrozoon ovis okozta megbetegedésének hazai megállapítása

Elozetes közlemény

Translated title of the contribution: Diagnosis of Eperythrozoon ovis infection in sheep in Hungary. Preliminary publication

Hajtós István, Glávits Róbert, Erdos András, V. Pálfi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Between August and November 1997, a disease manifesting in severe anaemia, submandibular oedema (Figure 1), fatigue, dullness, hyperthermia (by about 0,5-1 °C), inappetence and progressive emaciation was noted in a flock of 412 sheep in Northern Hungary. Mainly 14-15-month-old yearling tegs were affected, but 2-7-year-old ewes and breeding rams also succumbed to the disease. During this time 35 (8.5%) animals got ill and 9 (2.2%) died. Therapy was attempted unsuccessfully at first with amoxicillin, but a long-acting oxytetracycline product administered twice in three days intervals at a dose 20 mg/kg body weight, complemented by a dose of ivermectin (0,5 mg/25 kg body weight) and in severe cases with cardiotonics (coffein + digitoxin), proved effective. Weeks after their recovery, the animals showed fleece loss without any inflammatory skin changes (Figure 2). Blood smears of six untreated sheep stained after Giemsa (Figure 3 and 4) and transmission electron microscopy (Figures 5 and 6) showed 0.3-0.7 μm big rickettsiae, identified as Eperythrozoon ovis. The proportion of infected red blood cells in the smear samples ranged from 20 to 60%. Other main haematological values of the anticoagulant-treated blood samples from the untreated sick sheep were: red blood cells - 1.9-4.7 T/l, white blood cells 19.6-51 G/l, lymphocyte ratio - 93-3-97.6, haemoglobin concentration - 0.1-5.7 g/dl, PCV - 10.9-17.5% (Table). Anaplasmosis, babesiosis and leptospirosis were excluded from the list of differential diagnoses through laboratory tests. The predisposing role of gastro-intestinal parasites, sarcocystiosis and border disease/bovine virus diarrhoea (BD/BVD) virus infection in the development of eperythrozoonosis was confirmed in the flock. For example, seven of nine blood samples (77.7%) taken from sick and asymptomatic yearling tegs were positive for BD/BVD virus infection.

Original languageHungarian
Pages (from-to)697-703
Number of pages7
JournalMagyar Allatorvosok Lapja
Volume120
Issue number11
Publication statusPublished - 1998

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Mycoplasma ovis
Hungary
Mycoplasma
border disease
Publications
Sheep
Border disease virus
bovine viral diarrhea
yearlings
sheep
blood
flocks
Virus Diseases
erythrocytes
digitoxin
Infection
infection
mycoplasmosis
Diarrhea
anaplasmosis

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Juhok Eperythrozoon ovis okozta megbetegedésének hazai megállapítása : Elozetes közlemény. / István, Hajtós; Róbert, Glávits; András, Erdos; Pálfi, V.

In: Magyar Allatorvosok Lapja, Vol. 120, No. 11, 1998, p. 697-703.

Research output: Contribution to journalArticle

István, Hajtós ; Róbert, Glávits ; András, Erdos ; Pálfi, V. / Juhok Eperythrozoon ovis okozta megbetegedésének hazai megállapítása : Elozetes közlemény. In: Magyar Allatorvosok Lapja. 1998 ; Vol. 120, No. 11. pp. 697-703.
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abstract = "Between August and November 1997, a disease manifesting in severe anaemia, submandibular oedema (Figure 1), fatigue, dullness, hyperthermia (by about 0,5-1 °C), inappetence and progressive emaciation was noted in a flock of 412 sheep in Northern Hungary. Mainly 14-15-month-old yearling tegs were affected, but 2-7-year-old ewes and breeding rams also succumbed to the disease. During this time 35 (8.5{\%}) animals got ill and 9 (2.2{\%}) died. Therapy was attempted unsuccessfully at first with amoxicillin, but a long-acting oxytetracycline product administered twice in three days intervals at a dose 20 mg/kg body weight, complemented by a dose of ivermectin (0,5 mg/25 kg body weight) and in severe cases with cardiotonics (coffein + digitoxin), proved effective. Weeks after their recovery, the animals showed fleece loss without any inflammatory skin changes (Figure 2). Blood smears of six untreated sheep stained after Giemsa (Figure 3 and 4) and transmission electron microscopy (Figures 5 and 6) showed 0.3-0.7 μm big rickettsiae, identified as Eperythrozoon ovis. The proportion of infected red blood cells in the smear samples ranged from 20 to 60{\%}. Other main haematological values of the anticoagulant-treated blood samples from the untreated sick sheep were: red blood cells - 1.9-4.7 T/l, white blood cells 19.6-51 G/l, lymphocyte ratio - 93-3-97.6, haemoglobin concentration - 0.1-5.7 g/dl, PCV - 10.9-17.5{\%} (Table). Anaplasmosis, babesiosis and leptospirosis were excluded from the list of differential diagnoses through laboratory tests. The predisposing role of gastro-intestinal parasites, sarcocystiosis and border disease/bovine virus diarrhoea (BD/BVD) virus infection in the development of eperythrozoonosis was confirmed in the flock. For example, seven of nine blood samples (77.7{\%}) taken from sick and asymptomatic yearling tegs were positive for BD/BVD virus infection.",
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