A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei

Translated title of the contribution: Diabetic neuropathy: Clinical importance and novel therapeutic approaches

P. Kempler, Putz Zsuzsanna, Istenes Ildikó, Németh Nóra, Keresztes Katalin, Körei Anna Erzsébet, Martos Tímea

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Key clinical characteristics of sensory, motor, autonomic and painful neuropathy are reviewed. In the case of small fiber neuropathy, besides classical neuropathic symptoms, results of different neuropathy assessments are negative. Most relevant diagnostic procedures are reviewed. If neuropathic damage is present but there are no symptoms, pathogenetic oriented causal treatment is suggested. The aim of pathogenetic oriented treatment is to slow down, stop or reverse the progression of neuropathy. Components of pathogenetic oriented treatment are glycaemic control, management of risk factors, benfotiamin and alpha-lipoic acid. Gabapentin, pregabalin and duloxetin should be considered as most efficient symptomatic treatment. If both neuropathic damage just as clinical symptoms of neuropathy are present, in many patients combination of pathogenetic oriented and symptomatic treatment should be preferred.

Original languageHungarian
Pages (from-to)155-162
Number of pages8
JournalOrvoskepzes
Volume85
Issue number2
Publication statusPublished - 2010

Fingerprint

Diabetic Neuropathies
Therapeutics
Thioctic Acid

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kempler, P., Zsuzsanna, P., Ildikó, I., Nóra, N., Katalin, K., Erzsébet, K. A., & Tímea, M. (2010). A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei. Orvoskepzes, 85(2), 155-162.

A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei. / Kempler, P.; Zsuzsanna, Putz; Ildikó, Istenes; Nóra, Németh; Katalin, Keresztes; Erzsébet, Körei Anna; Tímea, Martos.

In: Orvoskepzes, Vol. 85, No. 2, 2010, p. 155-162.

Research output: Contribution to journalArticle

Kempler, P, Zsuzsanna, P, Ildikó, I, Nóra, N, Katalin, K, Erzsébet, KA & Tímea, M 2010, 'A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei', Orvoskepzes, vol. 85, no. 2, pp. 155-162.
Kempler P, Zsuzsanna P, Ildikó I, Nóra N, Katalin K, Erzsébet KA et al. A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei. Orvoskepzes. 2010;85(2):155-162.
Kempler, P. ; Zsuzsanna, Putz ; Ildikó, Istenes ; Nóra, Németh ; Katalin, Keresztes ; Erzsébet, Körei Anna ; Tímea, Martos. / A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei. In: Orvoskepzes. 2010 ; Vol. 85, No. 2. pp. 155-162.
@article{e832e34564824d91b3a37592863ec05d,
title = "A diabeteses neuropathia klinikai jelentos{\'e}ge {\'e}s {\'u}jabb kezel{\'e}si lehetos{\'e}gei",
abstract = "Key clinical characteristics of sensory, motor, autonomic and painful neuropathy are reviewed. In the case of small fiber neuropathy, besides classical neuropathic symptoms, results of different neuropathy assessments are negative. Most relevant diagnostic procedures are reviewed. If neuropathic damage is present but there are no symptoms, pathogenetic oriented causal treatment is suggested. The aim of pathogenetic oriented treatment is to slow down, stop or reverse the progression of neuropathy. Components of pathogenetic oriented treatment are glycaemic control, management of risk factors, benfotiamin and alpha-lipoic acid. Gabapentin, pregabalin and duloxetin should be considered as most efficient symptomatic treatment. If both neuropathic damage just as clinical symptoms of neuropathy are present, in many patients combination of pathogenetic oriented and symptomatic treatment should be preferred.",
keywords = "Alpha-lipoic acid, Benfotiamin, Diabetic neuropathy, Sensory neuropathy, Small fiber neuropathy",
author = "P. Kempler and Putz Zsuzsanna and Istenes Ildik{\'o} and N{\'e}meth N{\'o}ra and Keresztes Katalin and Erzs{\'e}bet, {K{\"o}rei Anna} and Martos T{\'i}mea",
year = "2010",
language = "Hungarian",
volume = "85",
pages = "155--162",
journal = "Orvoskepzes",
issn = "0030-6037",
publisher = "Semmelweis Kiado",
number = "2",

}

TY - JOUR

T1 - A diabeteses neuropathia klinikai jelentosége és újabb kezelési lehetoségei

AU - Kempler, P.

AU - Zsuzsanna, Putz

AU - Ildikó, Istenes

AU - Nóra, Németh

AU - Katalin, Keresztes

AU - Erzsébet, Körei Anna

AU - Tímea, Martos

PY - 2010

Y1 - 2010

N2 - Key clinical characteristics of sensory, motor, autonomic and painful neuropathy are reviewed. In the case of small fiber neuropathy, besides classical neuropathic symptoms, results of different neuropathy assessments are negative. Most relevant diagnostic procedures are reviewed. If neuropathic damage is present but there are no symptoms, pathogenetic oriented causal treatment is suggested. The aim of pathogenetic oriented treatment is to slow down, stop or reverse the progression of neuropathy. Components of pathogenetic oriented treatment are glycaemic control, management of risk factors, benfotiamin and alpha-lipoic acid. Gabapentin, pregabalin and duloxetin should be considered as most efficient symptomatic treatment. If both neuropathic damage just as clinical symptoms of neuropathy are present, in many patients combination of pathogenetic oriented and symptomatic treatment should be preferred.

AB - Key clinical characteristics of sensory, motor, autonomic and painful neuropathy are reviewed. In the case of small fiber neuropathy, besides classical neuropathic symptoms, results of different neuropathy assessments are negative. Most relevant diagnostic procedures are reviewed. If neuropathic damage is present but there are no symptoms, pathogenetic oriented causal treatment is suggested. The aim of pathogenetic oriented treatment is to slow down, stop or reverse the progression of neuropathy. Components of pathogenetic oriented treatment are glycaemic control, management of risk factors, benfotiamin and alpha-lipoic acid. Gabapentin, pregabalin and duloxetin should be considered as most efficient symptomatic treatment. If both neuropathic damage just as clinical symptoms of neuropathy are present, in many patients combination of pathogenetic oriented and symptomatic treatment should be preferred.

KW - Alpha-lipoic acid

KW - Benfotiamin

KW - Diabetic neuropathy

KW - Sensory neuropathy

KW - Small fiber neuropathy

UR - http://www.scopus.com/inward/record.url?scp=82555198107&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82555198107&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:82555198107

VL - 85

SP - 155

EP - 162

JO - Orvoskepzes

JF - Orvoskepzes

SN - 0030-6037

IS - 2

ER -