Diabetes mellitus és fibrinolysis (tapasztalatok in vitro alvadék oldási próbával).

Translated title of the contribution: Diabetes mellitus and fibrinolysis (experience with an in vitro clot lysis test)

M. Udvardy, E. Pósán

Research output: Contribution to journalArticle

Abstract

After a concise review on fibrinolysis in diabetes mellitus, special attention is given to the observations suggesting impaired fibrinolysis in non-insulin dependent diabetes mellitus and in hyperinsulinaemia. This fibrinolytic defect, based mainly upon indirect data, may contribute to the development of macroangiopathy. The results discussed here, gained by a simple in vitro clot lysis assay revealed decreased fibrinolytic properties in some of the non-insulin dependent diabetic patients, however the mean value did not differ significantly from the control. The potential profibrinolytic effect of different antidiabetic treatment profibrinolytic effect of different antidiabetic treatment modalities also received attention. The clinical significance of the apparent alteration of fibrinolysis in diabetes mellitus should be evaluated appropriately as a part of a complex disturbance of haemostatic balance in diabetes mellitus. Further studies and improved fibrinolytic methods seems to be required to ascertain a causal relationship between altered fibrinolysis and diabetic vascular complications.

Translated title of the contributionDiabetes mellitus and fibrinolysis (experience with an in vitro clot lysis test)
Original languageHungarian
Pages (from-to)2025-2027
Number of pages3
JournalOrvosi hetilap
Volume135
Issue number37
Publication statusPublished - Sep 11 1994

ASJC Scopus subject areas

  • Medicine(all)

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