Devic-szindróma - Esetismertetés, valamint a diagnosztika és a kezelés aktuális elvei

Translated title of the contribution: Devic syndrome - Case report, diagnostic and therapeutic principles

Anna Iljlcsov, P. Barsi, György Várallyay, Erika Tátrai, G. M. Somfai, D. Bereczki, Gábor Rudas, Magdolna Simó

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Neuromyelitis optica (NMO, Devic-syndrome) is a rare, relapsing autoimmun disease of the central nervous system, which is distinguished from other demyelinating disorders by a recently identified, specific autoantibody. By demonstrating the anti-aquaporin-4 IgG in the serum, a heterogenous group of syndromes can be defined, called NMO-spectrum. In the future, optical coherence tomography may support this diagnosis besides the clinical features, imaging examinations and presence of serum antibody. Early recognition and treatment can improve clinical outcome even in serious condition. Long-term immunosuppressive therapy is advised to prevent further relapses and to stabilize or improve clinical status. Hereby, we report a case of a 51-year-old woman, under treatment for 1.5 years. We summarize the up-to-date knowledge about the pathomechanism, diagnostic strategy and therapy of neuromyelitis optica. We review recent findings and the diagnostic value of a new, non-invasive ophtalmological examination, the optical coherence tomography. According to the first results, this method may be helpful in the early differential diagnosis of optic neuritis.

Original languageHungarian
Pages (from-to)320-326
Number of pages7
JournalIdeggyógyászati szemle
Volume63
Issue number9-10
Publication statusPublished - Sep 30 2010

Fingerprint

Neuromyelitis Optica
Optical Coherence Tomography
Aquaporin 4
Optic Neuritis
Central Nervous System Diseases
Demyelinating Diseases
Therapeutics
Immunosuppressive Agents
Serum
Autoantibodies
Early Diagnosis
Differential Diagnosis
Immunoglobulin G
Recurrence
Antibodies

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Devic-szindróma - Esetismertetés, valamint a diagnosztika és a kezelés aktuális elvei. / Iljlcsov, Anna; Barsi, P.; Várallyay, György; Tátrai, Erika; Somfai, G. M.; Bereczki, D.; Rudas, Gábor; Simó, Magdolna.

In: Ideggyógyászati szemle, Vol. 63, No. 9-10, 30.09.2010, p. 320-326.

Research output: Contribution to journalArticle

Iljlcsov, A, Barsi, P, Várallyay, G, Tátrai, E, Somfai, GM, Bereczki, D, Rudas, G & Simó, M 2010, 'Devic-szindróma - Esetismertetés, valamint a diagnosztika és a kezelés aktuális elvei', Ideggyógyászati szemle, vol. 63, no. 9-10, pp. 320-326.
Iljlcsov, Anna ; Barsi, P. ; Várallyay, György ; Tátrai, Erika ; Somfai, G. M. ; Bereczki, D. ; Rudas, Gábor ; Simó, Magdolna. / Devic-szindróma - Esetismertetés, valamint a diagnosztika és a kezelés aktuális elvei. In: Ideggyógyászati szemle. 2010 ; Vol. 63, No. 9-10. pp. 320-326.
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