Development of specific populations of interneurons in the ventral horn of the embryonic chick lumbosacral spinal cord

M. Antal, E. Polgar, A. Berki, A. Birinyi, Z. Puskár

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The development, morphological and neurochemical properties of specific populations of interneurons were investigated in the ventral horn of the embryonic and mature chick lumbosacral spinal cord by using pre- and post-embedding immunocytochemical as well as anterograde axonal tracing techniques. We have identified and traced the morphological maturation of the following cell groups : (1) Neurons immunoreactive for calbindin-D 28k (CaB), a calcium-binding protein that has been reported to be a marker of certain subsets of excitatory spinal neurons. We have distinguished and traced the maturation of three CaB-immunoreactive cell groups in the ventral horn; (2) Neurons immunoreactive for GABA and glycine, the two putative inhibitory amino acid neurotransmitters in the spinal cord; (3) Neurons within the nucleus marginalis, a cell group located in the ventrolateral aspect of the white matter in close proximity to the lateral motor column. The characteristic features of the development of these neurons are discussed and correlated with previous neuroanatomical and physiological studies concerning motor functions in the developing chick spinal cord.

Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalEuropean Journal of Morphology
Volume32
Issue number2-4
Publication statusPublished - 1994

Fingerprint

interneurons
Interneurons
Horns
spinal cord
Spinal Cord
neurons
chicks
Neurons
Population
Calbindins
GABAergic Neurons
Calcium-Binding Proteins
calbindin
calcium-binding proteins
Glycine
gamma-aminobutyric acid
Neurotransmitter Agents
cells
neurotransmitters
glycine (amino acid)

Keywords

  • calcium-binding proteins
  • GABA
  • glycine
  • immunocytochemistry
  • neural tracing

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Anatomy

Cite this

Development of specific populations of interneurons in the ventral horn of the embryonic chick lumbosacral spinal cord. / Antal, M.; Polgar, E.; Berki, A.; Birinyi, A.; Puskár, Z.

In: European Journal of Morphology, Vol. 32, No. 2-4, 1994, p. 201-206.

Research output: Contribution to journalArticle

@article{aac201cf12444a3a885b6aa3927d2fc8,
title = "Development of specific populations of interneurons in the ventral horn of the embryonic chick lumbosacral spinal cord",
abstract = "The development, morphological and neurochemical properties of specific populations of interneurons were investigated in the ventral horn of the embryonic and mature chick lumbosacral spinal cord by using pre- and post-embedding immunocytochemical as well as anterograde axonal tracing techniques. We have identified and traced the morphological maturation of the following cell groups : (1) Neurons immunoreactive for calbindin-D 28k (CaB), a calcium-binding protein that has been reported to be a marker of certain subsets of excitatory spinal neurons. We have distinguished and traced the maturation of three CaB-immunoreactive cell groups in the ventral horn; (2) Neurons immunoreactive for GABA and glycine, the two putative inhibitory amino acid neurotransmitters in the spinal cord; (3) Neurons within the nucleus marginalis, a cell group located in the ventrolateral aspect of the white matter in close proximity to the lateral motor column. The characteristic features of the development of these neurons are discussed and correlated with previous neuroanatomical and physiological studies concerning motor functions in the developing chick spinal cord.",
keywords = "calcium-binding proteins, GABA, glycine, immunocytochemistry, neural tracing",
author = "M. Antal and E. Polgar and A. Berki and A. Birinyi and Z. Pusk{\'a}r",
year = "1994",
language = "English",
volume = "32",
pages = "201--206",
journal = "European Journal of Morphology",
issn = "0924-3860",
publisher = "Swets & Zeitlinger",
number = "2-4",

}

TY - JOUR

T1 - Development of specific populations of interneurons in the ventral horn of the embryonic chick lumbosacral spinal cord

AU - Antal, M.

AU - Polgar, E.

AU - Berki, A.

AU - Birinyi, A.

AU - Puskár, Z.

PY - 1994

Y1 - 1994

N2 - The development, morphological and neurochemical properties of specific populations of interneurons were investigated in the ventral horn of the embryonic and mature chick lumbosacral spinal cord by using pre- and post-embedding immunocytochemical as well as anterograde axonal tracing techniques. We have identified and traced the morphological maturation of the following cell groups : (1) Neurons immunoreactive for calbindin-D 28k (CaB), a calcium-binding protein that has been reported to be a marker of certain subsets of excitatory spinal neurons. We have distinguished and traced the maturation of three CaB-immunoreactive cell groups in the ventral horn; (2) Neurons immunoreactive for GABA and glycine, the two putative inhibitory amino acid neurotransmitters in the spinal cord; (3) Neurons within the nucleus marginalis, a cell group located in the ventrolateral aspect of the white matter in close proximity to the lateral motor column. The characteristic features of the development of these neurons are discussed and correlated with previous neuroanatomical and physiological studies concerning motor functions in the developing chick spinal cord.

AB - The development, morphological and neurochemical properties of specific populations of interneurons were investigated in the ventral horn of the embryonic and mature chick lumbosacral spinal cord by using pre- and post-embedding immunocytochemical as well as anterograde axonal tracing techniques. We have identified and traced the morphological maturation of the following cell groups : (1) Neurons immunoreactive for calbindin-D 28k (CaB), a calcium-binding protein that has been reported to be a marker of certain subsets of excitatory spinal neurons. We have distinguished and traced the maturation of three CaB-immunoreactive cell groups in the ventral horn; (2) Neurons immunoreactive for GABA and glycine, the two putative inhibitory amino acid neurotransmitters in the spinal cord; (3) Neurons within the nucleus marginalis, a cell group located in the ventrolateral aspect of the white matter in close proximity to the lateral motor column. The characteristic features of the development of these neurons are discussed and correlated with previous neuroanatomical and physiological studies concerning motor functions in the developing chick spinal cord.

KW - calcium-binding proteins

KW - GABA

KW - glycine

KW - immunocytochemistry

KW - neural tracing

UR - http://www.scopus.com/inward/record.url?scp=0027982316&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027982316&partnerID=8YFLogxK

M3 - Article

C2 - 7803167

AN - SCOPUS:0027982316

VL - 32

SP - 201

EP - 206

JO - European Journal of Morphology

JF - European Journal of Morphology

SN - 0924-3860

IS - 2-4

ER -