Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake

S. Ranka, J. M. Gee, L. Bíró, G. Brett, S. Saha, P. Kroon, J. Skinner, A. R. Hart, A. Cassidy, M. Rhodes, I. T. Johnson

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objectives: To measure the relationship between quercetin and naringenin intakes as estimated by food frequency questionnaire (FFQ), and the urinary excretion of quercetin and naringenin aglycones after their enzymatic hydrolysis in human volunteers. Subjects and methods: Volunteers were recruited via the Human Nutrition Unit volunteer databank at the Institute of Food Research, Norwich. Sixty-three volunteers were recruited into the study, of which 14 were excluded and 49 completed the study. A modified FFQ was developed and used to estimate daily intake of quercetin and naringenin in 49 healthy volunteers who also provided five 24-h urine samples over a 2-week period. Urinary excretion of quercetin and naringenin metabolites was determined by solid-phase extraction and high-pressure liquid chromatography. Results: The estimated mean intakes of quercetin and naringenin were 29.4mg (s.d. 15.0) and 58.1mg (s.d. 62.7) per day, respectively. Mean urinary excretion of quercetin was 60.1μg (s.d. 33.1) and that of naringenin was 0.56mg (s.d. 0.4). The correlation between FFQ estimated intake of quercetin and naringenin and levels excreted in the urine were r=0.82 (P

Original languageEnglish
Pages (from-to)1131-1138
Number of pages8
JournalEuropean Journal of Clinical Nutrition
Volume62
Issue number9
DOIs
Publication statusPublished - 2008

Fingerprint

naringenin
Quercetin
food frequency questionnaires
quercetin
volunteers
Food
Volunteers
excretion
urine
Urine
food research
Solid Phase Extraction
human nutrition
enzymatic hydrolysis
solid phase extraction
Surveys and Questionnaires
Healthy Volunteers
Hydrolysis
high performance liquid chromatography
High Pressure Liquid Chromatography

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake. / Ranka, S.; Gee, J. M.; Bíró, L.; Brett, G.; Saha, S.; Kroon, P.; Skinner, J.; Hart, A. R.; Cassidy, A.; Rhodes, M.; Johnson, I. T.

In: European Journal of Clinical Nutrition, Vol. 62, No. 9, 2008, p. 1131-1138.

Research output: Contribution to journalArticle

Ranka, S, Gee, JM, Bíró, L, Brett, G, Saha, S, Kroon, P, Skinner, J, Hart, AR, Cassidy, A, Rhodes, M & Johnson, IT 2008, 'Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake', European Journal of Clinical Nutrition, vol. 62, no. 9, pp. 1131-1138. https://doi.org/10.1038/sj.ejcn.1602827
Ranka, S. ; Gee, J. M. ; Bíró, L. ; Brett, G. ; Saha, S. ; Kroon, P. ; Skinner, J. ; Hart, A. R. ; Cassidy, A. ; Rhodes, M. ; Johnson, I. T. / Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake. In: European Journal of Clinical Nutrition. 2008 ; Vol. 62, No. 9. pp. 1131-1138.
@article{455b2d797eb24d43a191d97fa87b0e5d,
title = "Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake",
abstract = "Objectives: To measure the relationship between quercetin and naringenin intakes as estimated by food frequency questionnaire (FFQ), and the urinary excretion of quercetin and naringenin aglycones after their enzymatic hydrolysis in human volunteers. Subjects and methods: Volunteers were recruited via the Human Nutrition Unit volunteer databank at the Institute of Food Research, Norwich. Sixty-three volunteers were recruited into the study, of which 14 were excluded and 49 completed the study. A modified FFQ was developed and used to estimate daily intake of quercetin and naringenin in 49 healthy volunteers who also provided five 24-h urine samples over a 2-week period. Urinary excretion of quercetin and naringenin metabolites was determined by solid-phase extraction and high-pressure liquid chromatography. Results: The estimated mean intakes of quercetin and naringenin were 29.4mg (s.d. 15.0) and 58.1mg (s.d. 62.7) per day, respectively. Mean urinary excretion of quercetin was 60.1μg (s.d. 33.1) and that of naringenin was 0.56mg (s.d. 0.4). The correlation between FFQ estimated intake of quercetin and naringenin and levels excreted in the urine were r=0.82 (P",
author = "S. Ranka and Gee, {J. M.} and L. B{\'i}r{\'o} and G. Brett and S. Saha and P. Kroon and J. Skinner and Hart, {A. R.} and A. Cassidy and M. Rhodes and Johnson, {I. T.}",
year = "2008",
doi = "10.1038/sj.ejcn.1602827",
language = "English",
volume = "62",
pages = "1131--1138",
journal = "European Journal of Clinical Nutrition",
issn = "0954-3007",
publisher = "Nature Publishing Group",
number = "9",

}

TY - JOUR

T1 - Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake

AU - Ranka, S.

AU - Gee, J. M.

AU - Bíró, L.

AU - Brett, G.

AU - Saha, S.

AU - Kroon, P.

AU - Skinner, J.

AU - Hart, A. R.

AU - Cassidy, A.

AU - Rhodes, M.

AU - Johnson, I. T.

PY - 2008

Y1 - 2008

N2 - Objectives: To measure the relationship between quercetin and naringenin intakes as estimated by food frequency questionnaire (FFQ), and the urinary excretion of quercetin and naringenin aglycones after their enzymatic hydrolysis in human volunteers. Subjects and methods: Volunteers were recruited via the Human Nutrition Unit volunteer databank at the Institute of Food Research, Norwich. Sixty-three volunteers were recruited into the study, of which 14 were excluded and 49 completed the study. A modified FFQ was developed and used to estimate daily intake of quercetin and naringenin in 49 healthy volunteers who also provided five 24-h urine samples over a 2-week period. Urinary excretion of quercetin and naringenin metabolites was determined by solid-phase extraction and high-pressure liquid chromatography. Results: The estimated mean intakes of quercetin and naringenin were 29.4mg (s.d. 15.0) and 58.1mg (s.d. 62.7) per day, respectively. Mean urinary excretion of quercetin was 60.1μg (s.d. 33.1) and that of naringenin was 0.56mg (s.d. 0.4). The correlation between FFQ estimated intake of quercetin and naringenin and levels excreted in the urine were r=0.82 (P

AB - Objectives: To measure the relationship between quercetin and naringenin intakes as estimated by food frequency questionnaire (FFQ), and the urinary excretion of quercetin and naringenin aglycones after their enzymatic hydrolysis in human volunteers. Subjects and methods: Volunteers were recruited via the Human Nutrition Unit volunteer databank at the Institute of Food Research, Norwich. Sixty-three volunteers were recruited into the study, of which 14 were excluded and 49 completed the study. A modified FFQ was developed and used to estimate daily intake of quercetin and naringenin in 49 healthy volunteers who also provided five 24-h urine samples over a 2-week period. Urinary excretion of quercetin and naringenin metabolites was determined by solid-phase extraction and high-pressure liquid chromatography. Results: The estimated mean intakes of quercetin and naringenin were 29.4mg (s.d. 15.0) and 58.1mg (s.d. 62.7) per day, respectively. Mean urinary excretion of quercetin was 60.1μg (s.d. 33.1) and that of naringenin was 0.56mg (s.d. 0.4). The correlation between FFQ estimated intake of quercetin and naringenin and levels excreted in the urine were r=0.82 (P

UR - http://www.scopus.com/inward/record.url?scp=51549085614&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51549085614&partnerID=8YFLogxK

U2 - 10.1038/sj.ejcn.1602827

DO - 10.1038/sj.ejcn.1602827

M3 - Article

VL - 62

SP - 1131

EP - 1138

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

SN - 0954-3007

IS - 9

ER -