Deuteron-induced reactions on Yb: Measured cross sections and rationale for production pathways of carrier-free, medically relevant radionuclides

A. Hermanne, S. Takács, M. B. Goldberg, E. Lavie, Yu N. Shubin, S. Kovalev

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Deuteron-induced nuclear reactions for generation of carrier-free Lu isotopes were investigated using the stacked-foil activation technique on natural Yb targets at incident energies up to Ed = 20 MeV. Excitation functions are reported for the first time for the generation of 170,171m+g,172m+g,173,174g,177gLu and 169cum,175,177g+mYb. Special attention is paid to cumulative, direct and indirect production of the therapeutically-relevant radioisotope 177gLu via the 176Yb(d, p)177Yb → 177Lu and 176Yb(d, n)177Lu reactions. Thick target yields for all investigated radionuclides, optimal irradiation conditions and comparison of production routes for the medically-relevant isotopes are derived.

Original languageEnglish
Pages (from-to)223-231
Number of pages9
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume247
Issue number2
DOIs
Publication statusPublished - Jun 2006

Fingerprint

Deuterium
Radioisotopes
Isotopes
radioactive isotopes
deuterons
isotopes
Nuclear reactions
cross sections
nuclear reactions
Metal foil
foils
Chemical activation
routes
Irradiation
activation
irradiation
excitation
energy

Keywords

  • Lu
  • Carrier-free Lu radionuclides
  • Deuteron-induced reactions
  • Experimental cross sections
  • Model calculations
  • Thick target yields
  • Yb targets

ASJC Scopus subject areas

  • Surfaces, Coatings and Films
  • Instrumentation
  • Surfaces and Interfaces

Cite this

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title = "Deuteron-induced reactions on Yb: Measured cross sections and rationale for production pathways of carrier-free, medically relevant radionuclides",
abstract = "Deuteron-induced nuclear reactions for generation of carrier-free Lu isotopes were investigated using the stacked-foil activation technique on natural Yb targets at incident energies up to Ed = 20 MeV. Excitation functions are reported for the first time for the generation of 170,171m+g,172m+g,173,174g,177gLu and 169cum,175,177g+mYb. Special attention is paid to cumulative, direct and indirect production of the therapeutically-relevant radioisotope 177gLu via the 176Yb(d, p)177Yb → 177Lu and 176Yb(d, n)177Lu reactions. Thick target yields for all investigated radionuclides, optimal irradiation conditions and comparison of production routes for the medically-relevant isotopes are derived.",
keywords = "Lu, Carrier-free Lu radionuclides, Deuteron-induced reactions, Experimental cross sections, Model calculations, Thick target yields, Yb targets",
author = "A. Hermanne and S. Tak{\'a}cs and Goldberg, {M. B.} and E. Lavie and Shubin, {Yu N.} and S. Kovalev",
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T2 - Measured cross sections and rationale for production pathways of carrier-free, medically relevant radionuclides

AU - Hermanne, A.

AU - Takács, S.

AU - Goldberg, M. B.

AU - Lavie, E.

AU - Shubin, Yu N.

AU - Kovalev, S.

PY - 2006/6

Y1 - 2006/6

N2 - Deuteron-induced nuclear reactions for generation of carrier-free Lu isotopes were investigated using the stacked-foil activation technique on natural Yb targets at incident energies up to Ed = 20 MeV. Excitation functions are reported for the first time for the generation of 170,171m+g,172m+g,173,174g,177gLu and 169cum,175,177g+mYb. Special attention is paid to cumulative, direct and indirect production of the therapeutically-relevant radioisotope 177gLu via the 176Yb(d, p)177Yb → 177Lu and 176Yb(d, n)177Lu reactions. Thick target yields for all investigated radionuclides, optimal irradiation conditions and comparison of production routes for the medically-relevant isotopes are derived.

AB - Deuteron-induced nuclear reactions for generation of carrier-free Lu isotopes were investigated using the stacked-foil activation technique on natural Yb targets at incident energies up to Ed = 20 MeV. Excitation functions are reported for the first time for the generation of 170,171m+g,172m+g,173,174g,177gLu and 169cum,175,177g+mYb. Special attention is paid to cumulative, direct and indirect production of the therapeutically-relevant radioisotope 177gLu via the 176Yb(d, p)177Yb → 177Lu and 176Yb(d, n)177Lu reactions. Thick target yields for all investigated radionuclides, optimal irradiation conditions and comparison of production routes for the medically-relevant isotopes are derived.

KW - Lu

KW - Carrier-free Lu radionuclides

KW - Deuteron-induced reactions

KW - Experimental cross sections

KW - Model calculations

KW - Thick target yields

KW - Yb targets

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