Determination of Pt Concentration in Cervical Tumor Tissues Using Energy-Dispersive X-Ray-Fluorescence (EDXRF) Method

K. L. Szluha, I. Uzonyi, J. Bacso, L. Lampe, I. Czifra, M. Peter, C. Villena, W. Schmidt

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Biopsy samples taken from cervical cancer patients after intraarterial and intravenous administration of Cisplatin were analyzed by the energy-dispersive x-ray fluorescence (EDXRF) method. Distribution of platinum (Pt) within the tumor and in its proximity was studied. Pt concentration seems to depend on the mode of administration. Intraarterial administration of Cisplatin resulted in seven times higher Pt concentration in the tumor tissue than the intravenous administration. EDXRF proved to be a useful tool for the determination of Pt in biopsy tissues.

Original languageEnglish
Pages (from-to)238-244
Number of pages7
JournalMicrochemical Journal
Volume51
Issue number1-2
DOIs
Publication statusPublished - Feb 1995

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Platinum
Tumors
Fluorescence
Tissue
X rays
Biopsy
Cisplatin

ASJC Scopus subject areas

  • Spectroscopy
  • Analytical Chemistry

Cite this

Determination of Pt Concentration in Cervical Tumor Tissues Using Energy-Dispersive X-Ray-Fluorescence (EDXRF) Method. / Szluha, K. L.; Uzonyi, I.; Bacso, J.; Lampe, L.; Czifra, I.; Peter, M.; Villena, C.; Schmidt, W.

In: Microchemical Journal, Vol. 51, No. 1-2, 02.1995, p. 238-244.

Research output: Contribution to journalArticle

Szluha, K. L. ; Uzonyi, I. ; Bacso, J. ; Lampe, L. ; Czifra, I. ; Peter, M. ; Villena, C. ; Schmidt, W. / Determination of Pt Concentration in Cervical Tumor Tissues Using Energy-Dispersive X-Ray-Fluorescence (EDXRF) Method. In: Microchemical Journal. 1995 ; Vol. 51, No. 1-2. pp. 238-244.
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AU - Villena, C.

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