Determination of oxytetracycline and its decomposition products in Tetran vulnerary powder

Gy Morovjan, E. Horvath, I. Vagi, J. Fekete

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A simple and fast HPLC method was developed for the determination of oxytetracycline and its decomposition products in pharmaceutical preparations. For this purpose an octadecyl modified silica stationary phase and a terner eluent containing acetonitrile-methanol-aqueous oxalic acid/EDTA solution was employed. Using this method, a stability study of oxytetracycline-containing powder was carried out. In this paper the analytical method and its performance data, the sample preparation and the obtained stability data are presented. The literature published on this topic is also shortly overviewed and discussed.

Original languageEnglish
Pages (from-to)67-73
Number of pages7
JournalActa Pharmaceutica Hungarica
Volume64
Issue number2
Publication statusPublished - 1994

Fingerprint

Oxytetracycline
Powders
Oxalic Acid
Edetic Acid
Silicon Dioxide
Methanol
High Pressure Liquid Chromatography
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Determination of oxytetracycline and its decomposition products in Tetran vulnerary powder. / Morovjan, Gy; Horvath, E.; Vagi, I.; Fekete, J.

In: Acta Pharmaceutica Hungarica, Vol. 64, No. 2, 1994, p. 67-73.

Research output: Contribution to journalArticle

@article{1b74308438514fba9b99140639bfa54f,
title = "Determination of oxytetracycline and its decomposition products in Tetran vulnerary powder",
abstract = "A simple and fast HPLC method was developed for the determination of oxytetracycline and its decomposition products in pharmaceutical preparations. For this purpose an octadecyl modified silica stationary phase and a terner eluent containing acetonitrile-methanol-aqueous oxalic acid/EDTA solution was employed. Using this method, a stability study of oxytetracycline-containing powder was carried out. In this paper the analytical method and its performance data, the sample preparation and the obtained stability data are presented. The literature published on this topic is also shortly overviewed and discussed.",
author = "Gy Morovjan and E. Horvath and I. Vagi and J. Fekete",
year = "1994",
language = "English",
volume = "64",
pages = "67--73",
journal = "Acta Pharmaceutica Hungarica",
issn = "0001-6659",
publisher = "Magyar Gyogyszereszeti Tarsasag",
number = "2",

}

TY - JOUR

T1 - Determination of oxytetracycline and its decomposition products in Tetran vulnerary powder

AU - Morovjan, Gy

AU - Horvath, E.

AU - Vagi, I.

AU - Fekete, J.

PY - 1994

Y1 - 1994

N2 - A simple and fast HPLC method was developed for the determination of oxytetracycline and its decomposition products in pharmaceutical preparations. For this purpose an octadecyl modified silica stationary phase and a terner eluent containing acetonitrile-methanol-aqueous oxalic acid/EDTA solution was employed. Using this method, a stability study of oxytetracycline-containing powder was carried out. In this paper the analytical method and its performance data, the sample preparation and the obtained stability data are presented. The literature published on this topic is also shortly overviewed and discussed.

AB - A simple and fast HPLC method was developed for the determination of oxytetracycline and its decomposition products in pharmaceutical preparations. For this purpose an octadecyl modified silica stationary phase and a terner eluent containing acetonitrile-methanol-aqueous oxalic acid/EDTA solution was employed. Using this method, a stability study of oxytetracycline-containing powder was carried out. In this paper the analytical method and its performance data, the sample preparation and the obtained stability data are presented. The literature published on this topic is also shortly overviewed and discussed.

UR - http://www.scopus.com/inward/record.url?scp=0028358466&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028358466&partnerID=8YFLogxK

M3 - Article

C2 - 8017211

AN - SCOPUS:0028358466

VL - 64

SP - 67

EP - 73

JO - Acta Pharmaceutica Hungarica

JF - Acta Pharmaceutica Hungarica

SN - 0001-6659

IS - 2

ER -