Determination of gold accumulation in human tissues caused by gold therapy using x-ray fluorescence analysis

József Bacsó, I. Uzonyi, B. Dezső

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Human autopsy tissues from five patients with rheumatoid arthritis, who had been treated with aqueous solutions of gold and from an untreated control cadaver with the same disease, were analysed by x-ray fluorescence spectrometry using a conventional Si(Li) detection system. The gold and zinc concentrations of tissues were determined and compared to some results available in the literature. Correlation has been found between Zn and Au concentrations in heart, lung, kidney and liver tissues.

Original languageEnglish
Pages (from-to)323-326
Number of pages4
JournalInternational Journal of Radiation Applications and Instrumentation. Part
Volume39
Issue number4
DOIs
Publication statusPublished - 1988

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x ray fluorescence
therapy
gold
autopsies
arthritis
kidneys
liver
lungs
zinc
aqueous solutions
spectroscopy

ASJC Scopus subject areas

  • Radiation

Cite this

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abstract = "Human autopsy tissues from five patients with rheumatoid arthritis, who had been treated with aqueous solutions of gold and from an untreated control cadaver with the same disease, were analysed by x-ray fluorescence spectrometry using a conventional Si(Li) detection system. The gold and zinc concentrations of tissues were determined and compared to some results available in the literature. Correlation has been found between Zn and Au concentrations in heart, lung, kidney and liver tissues.",
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AB - Human autopsy tissues from five patients with rheumatoid arthritis, who had been treated with aqueous solutions of gold and from an untreated control cadaver with the same disease, were analysed by x-ray fluorescence spectrometry using a conventional Si(Li) detection system. The gold and zinc concentrations of tissues were determined and compared to some results available in the literature. Correlation has been found between Zn and Au concentrations in heart, lung, kidney and liver tissues.

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