Determination of endogenous formaldehyde level in human blood and urine by dimedone-14C radiometric method

T. Szarvas, E. Szatlóczky, J. Volford, L. Trézl, E. Tyihák, I. Rusznák

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Radiometric method was developed for the analysis of endogenous formaldehyde in human blood and urine using dimedone-14C reagent. The method based on that dimedone /5,5-dimethyl-cyclohexane-1, 3-dione/ can very easily condense with formaldehyde and other aldehydes. With the help of this radiometric method a sensitive technique and a more accurate evaluation have been made possible. Applying this method it could be established that the formaldehyde level in the blood varies between 0.4-0.6 μg ml-1 and in urine 2.5-4.0 μg ml-1. The error of determination and the chemical bonds of formaldehyde in the biological fluids are discussed.

Original languageEnglish
Pages (from-to)357-367
Number of pages11
JournalJournal of Radioanalytical and Nuclear Chemistry Letters
Volume106
Issue number6
DOIs
Publication statusPublished - Oct 1 1986

ASJC Scopus subject areas

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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