Determination of endogenous formaldehyde level in human blood and urine by dimedone-14C radiometric method

T. Szarvas, E. Szatlóczky, J. Volford, L. Trézl, E. Tyihák, I. Rusznák

Research output: Contribution to journalArticle

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Abstract

Radiometric method was developed for the analysis of endogenous formaldehyde in human blood and urine using dimedone-14C reagent. The method based on that dimedone /5,5-dimethyl-cyclohexane-1, 3-dione/ can very easily condense with formaldehyde and other aldehydes. With the help of this radiometric method a sensitive technique and a more accurate evaluation have been made possible. Applying this method it could be established that the formaldehyde level in the blood varies between 0.4-0.6 μg ml-1 and in urine 2.5-4.0 μg ml-1. The error of determination and the chemical bonds of formaldehyde in the biological fluids are discussed.

Original languageEnglish
Pages (from-to)357-367
Number of pages11
JournalJournal of Radioanalytical and Nuclear Chemistry
Volume106
Issue number6
DOIs
Publication statusPublished - Oct 1986

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Formaldehyde
Blood
Urine
Chemical bonds
Cyclohexane
Aldehydes
Fluids
dimedone

ASJC Scopus subject areas

  • Nuclear Energy and Engineering
  • Inorganic Chemistry
  • Analytical Chemistry

Cite this

Determination of endogenous formaldehyde level in human blood and urine by dimedone-14C radiometric method. / Szarvas, T.; Szatlóczky, E.; Volford, J.; Trézl, L.; Tyihák, E.; Rusznák, I.

In: Journal of Radioanalytical and Nuclear Chemistry, Vol. 106, No. 6, 10.1986, p. 357-367.

Research output: Contribution to journalArticle

Szarvas, T. ; Szatlóczky, E. ; Volford, J. ; Trézl, L. ; Tyihák, E. ; Rusznák, I. / Determination of endogenous formaldehyde level in human blood and urine by dimedone-14C radiometric method. In: Journal of Radioanalytical and Nuclear Chemistry. 1986 ; Vol. 106, No. 6. pp. 357-367.
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