INVAZIV EMLORAKOK SZOVETTANI DIFFERENCIACIOJANAK MEGHATAROZASA ES JELENTOSEGE

Translated title of the contribution: Determination and importance of the histological grade of invasive breast cancers

Research output: Contribution to journalReview article

Abstract

The histological grade of invasive breast cancers reflecting their differentiation is a proven prognostic marker, that may have its role in planning treatment. The belief of a poor reproducibility has prevented its wide use, this is why several changes have been made to improve the reproducibility. The article describes the modifications made in Nottingham to the most widely used scheme originated from Bloom and Richardson. It also gives illustrations essential for using this method. Besides methodology the article also describes some criticisms of histological grading, and its prognostic use as well as its relationship with other prognostic factors, eg. those related to proliferating activity, oncogenes, tumor suppressor genes and steroid hormon receptors.

Original languageHungarian
Pages (from-to)214-223
Number of pages10
JournalLege Artis Medicinae
Volume6
Issue number3-4
Publication statusPublished - May 20 1996

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ASJC Scopus subject areas

  • Medicine(all)

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