Detection of low molecular weight toxins using an optical phase method of ellipsometry

A. Nabok, A. Tsargorodskaya, M. K. Mustafa, I. Székács, N. F. Starodub, A. Székács

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The method of total internal reflection ellipsometry (TIRE), which records simultaneously two parameters Δ and Ψ related to the amplitudes and phases of p- and s-components of polarised light, respectively, was exploited here for detection of mycotoxins (T-2 and zearalenone). The above mycotoxins in sub-ppb concentrations were detected using TIRE in both direct and competitive immunoassay. The study of immune reaction kinetics allowed the evaluation of adsorption/desorption rates and the association constant for zearalenone. The investigation of grain products samples revealed the presence of high concentrations of T-2 (>600 ng/ml) in mould products.

Original languageEnglish
Pages (from-to)232-237
Number of pages6
JournalSensors and Actuators, B: Chemical
Volume154
Issue number2
DOIs
Publication statusPublished - Jun 20 2011

Fingerprint

Zearalenone
Mycotoxins
Ellipsometry
low molecular weights
ellipsometry
Molecular weight
Antigen-antibody reactions
immunoassay
Light polarization
products
Reaction kinetics
polarized light
Desorption
reaction kinetics
desorption
Association reactions
Adsorption
adsorption
evaluation

Keywords

  • Competitive immunoassay
  • Direct immunoassay
  • Kinetics of immune reaction
  • Spectroscopic ellipsometry
  • Total Internal Reflection Ellipsometry

ASJC Scopus subject areas

  • Instrumentation
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

Cite this

Detection of low molecular weight toxins using an optical phase method of ellipsometry. / Nabok, A.; Tsargorodskaya, A.; Mustafa, M. K.; Székács, I.; Starodub, N. F.; Székács, A.

In: Sensors and Actuators, B: Chemical, Vol. 154, No. 2, 20.06.2011, p. 232-237.

Research output: Contribution to journalArticle

Nabok, A. ; Tsargorodskaya, A. ; Mustafa, M. K. ; Székács, I. ; Starodub, N. F. ; Székács, A. / Detection of low molecular weight toxins using an optical phase method of ellipsometry. In: Sensors and Actuators, B: Chemical. 2011 ; Vol. 154, No. 2. pp. 232-237.
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