The presence of the highly pathogenic H5N1 avian influenza virus was examined with an immunohistochemical (IH) method in different organs of a mute swan (Cygnus olor) that died of the infection. The virus was detected in formaline-fixed and paraffin-embedded tissue samples of the brain, pancreas, liver, spleen, lung and small intestine, and mostly in the nucleus of different cell types by murine monoclonal antibodies specific for the nucleoprotein of type A influenza virus. The virus could be found in large amounts primarily in the brain. To the authors knowledge, avian influenza virus was demonstrated for the first time in the mute swan by immunohistochemistry.
|Translated title of the contribution||Detection of highly pathogenic avian influenza virus, H5N1 with immunohistochemical method in mute swan (Cygnus olor)|
|Number of pages||5|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 1 2007|
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