A Helicobacter pylori kimutatása gyomorcarcinomás szöveti mintákban.

Translated title of the contribution: Detection of Helicobacter pylori in tissue samples of stomach cancer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The role of Helicobacter pylori in the carcinogenesis of the stomach has been recognised both in intestinal and diffuse forms. The occurrence of the bacterium was studied in this report, with various methods in biopsy samples from the cancerous stomach, as well as the presence of associated gastritis and metaplasia related to the histological type. Retrospective histological examination were performed on endoscopic biopsy samples from 124 patients with distal stomach cancer using haematoxillin-eosin and Giemsa staining and immunohistochemical tests. Out of the 124 samples 69 (55.64%) was positive: 48 with Giemsa staining and further 21 samples showed immunohistochemical positivity on atrophic gastritis samples despite negative Giemsa staining. In view of the presence of gastritis and metaplasia significant difference (p < 0.001) was found between the positive and negative cases. The ratio of the Helicobacter pylori positive samples was high both for intestinal and diffuse type carcinomas. Our results suggest that the presence of Helicobacter pylori infection is important in the development of both types of carcinoma, nevertheless, the hystological type of the tumor is also decisively influenced by the onset of action of other more direct local eliciting factors.

Translated title of the contributionDetection of Helicobacter pylori in tissue samples of stomach cancer
Original languageHungarian
Pages (from-to)1985-1989
Number of pages5
JournalOrvosi hetilap
Volume140
Issue number36
Publication statusPublished - Sep 5 1999

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Detection of Helicobacter pylori in tissue samples of stomach cancer'. Together they form a unique fingerprint.

  • Cite this