Detection of carotid artery stenosis by in vivo duplex ultrasound: Correlation with planimetric measurements of the corresponding postmortem specimens

Gernot Schulte-Altedorneburg, Dirk W. Droste, S. Felszeghy, L. Csiba, Vasile Popa, Katalin Hegedüs, J. Kollár, László Módis, E. Bernd Ringelstein

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background and Purpose - The correct detection and quantification of carotid artery disease are of decisive impact on patient prognosis and adequate treatment. In this study, we evaluated the ability of ultrasonography to detect and to grade carotid artery stenosis through a comparison of the in vivo ultrasound findings with the planimetric analysis of the corresponding postmortem specimens. Methods - Shortly before their death, 59 critically ill neurological patients (mean age, 70 years) were prospectively examined by extracranial and intracranial Doppler sonography and color-coded duplex ultrasound. Carotid stenosis was classified by hemodynamic and morphological ultrasound criteria. Carotid specimens were removed in toto during autopsy. Under standardized conditions, specimens were redistended, sectioned, and histologically processed. Computerized planimetric measurements of the arteries were carried out and compared with the ultrasound findings. Correlation of the ultrasound and postmortem planimetric findings was available in 93 carotid bifurcations. Results - Through both techniques, 46 carotid arteries were found to be normal. Steno-occlusive carotid lesions ranged from 8.5% to 100% lumen reduction. Overall, r=0.96 and adjusted R2=0.90. For the steno-occlusive carotid lesions, r=0.91. Conclusions - Extracranial and intracranial Doppler and color-coded duplex ultrasound permits reliable detection and quantification of carotid artery stenoses and occlusions even under difficult examination conditions in critically ill patients.

Original languageEnglish
Pages (from-to)2402-2407
Number of pages6
JournalStroke
Volume33
Issue number10
DOIs
Publication statusPublished - Oct 1 2002

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Carotid Stenosis
Critical Illness
Color
Doppler Ultrasonography
Carotid Artery Diseases
Carotid Arteries
Autopsy
Ultrasonography
Arteries
Hemodynamics
Therapeutics

Keywords

  • Carotid arteries
  • Diagnosis
  • Pathology
  • Ultrasonography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

Cite this

Detection of carotid artery stenosis by in vivo duplex ultrasound : Correlation with planimetric measurements of the corresponding postmortem specimens. / Schulte-Altedorneburg, Gernot; Droste, Dirk W.; Felszeghy, S.; Csiba, L.; Popa, Vasile; Hegedüs, Katalin; Kollár, J.; Módis, László; Ringelstein, E. Bernd.

In: Stroke, Vol. 33, No. 10, 01.10.2002, p. 2402-2407.

Research output: Contribution to journalArticle

Schulte-Altedorneburg, Gernot ; Droste, Dirk W. ; Felszeghy, S. ; Csiba, L. ; Popa, Vasile ; Hegedüs, Katalin ; Kollár, J. ; Módis, László ; Ringelstein, E. Bernd. / Detection of carotid artery stenosis by in vivo duplex ultrasound : Correlation with planimetric measurements of the corresponding postmortem specimens. In: Stroke. 2002 ; Vol. 33, No. 10. pp. 2402-2407.
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