Detection of bovine herpesvirus 4 in aborted bovine placentas

Zoltán Deim, Levente Szeredi, Veronika Tompó, László Egyed

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Diagnostic studies on aborted placentas of cattle usually do not determine any reason for abortions. In this paper, five bovine herpesviruses (BoHVs) and some bacteriological agents were investigated by several methods in 33 aborted bovine placentas. Inclusion bodies, PCR and in situ DNA hybridization proved the presence of BoHV-4 DNA in six (18.18%) tested placentas. Positive DNA hybridization signal localized BoHV-4 DNA to placental epithelial cells macrophages and lymphocytes. By destroying epithelial cells and provoking local immune response BoHV-4 infection may inhibit physiological functions of the placenta during gestation. This finding is a further sign that BoHV-4 plays an active role in reproductive disorders of cattle.

Original languageEnglish
Pages (from-to)144-148
Number of pages5
JournalMicrobial Pathogenesis
Volume41
Issue number4-5
DOIs
Publication statusPublished - Oct 1 2006

Keywords

  • Aborted bovine placentas
  • Bovine herpesvirus 4
  • DNA hybridization
  • PCR

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

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