Detection by radioimmunoassay of antigens related to the P30 polypeptides of primate type C oncoviruses in peripheral leukocytes from patients with chronic myelogenous leukaemia

F. Tóth, L. Vaczi, J. Kiss, A. Réthy, K. Rák

Research output: Contribution to journalArticle

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Abstract

Leukocytes from patients with chronic myelogenous leukaemia were examined for antigens related to the p30 polypeptides of baboon endogenous virus (BaEV) and gibbon ape leukaemia virus (GaLV). Samples from patients with the quiescent phase of the disease proved to be negative or contained p30 of BaEV as the only viral antigen. In cases of blastoid crisis or acceleration, an antigen related to p30 of GaLV could be detected. In 5 of 6 patients, acceleration or blastoid crisis was preceded by expression of GaLV p30.

Original languageEnglish
Pages (from-to)376-380
Number of pages5
JournalActa Virologica
Volume25
Issue number6
Publication statusPublished - 1981

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Gibbon ape leukemia virus
Retroviridae
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Primates
Radioimmunoassay
Leukocytes
Papio
Antigens
Viruses
Viral Antigens
Peptides
polypeptide C

ASJC Scopus subject areas

  • Virology
  • Immunology

Cite this

Detection by radioimmunoassay of antigens related to the P30 polypeptides of primate type C oncoviruses in peripheral leukocytes from patients with chronic myelogenous leukaemia. / Tóth, F.; Vaczi, L.; Kiss, J.; Réthy, A.; Rák, K.

In: Acta Virologica, Vol. 25, No. 6, 1981, p. 376-380.

Research output: Contribution to journalArticle

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