Desmoplastic small round cell tumour of the pleura: A case report with unusual follow-up

G. Ostoros, Zsolt Orosz, Gábor Kovács, Ilona Soltész

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

In 1994 a 19-year-old woman presented with a few weeks history of back ache. Routine chest X-ray and CT examination revealed a lesion originating from the parietal pleura and destroying the ribs. The tumour was resected during thoracotomy. The histological examination raised the possibility of atypical carcinoid tumour. One year later the tumour recurred. After its re-resection, the patient received radiotherapy. Three years after the initial presentation multiple pulmonary metastases developed. The patient was treated with chemotherapy, receiving vincristine, epi-adriamycin and cyclophosphamide in 8 cycles, which resulted in complete remission. Between 1998 and 1999 progressions and partial remissions were observed, while the patient received further cycles of chemotherapy. Histological revision was performed in 1999 and a final diagnosis of desmoplastic small round cell tumour of the pleura was made. Immunohistochemically co-expression of cytokeratin, vimentin, desmin, and NSE was observed. The patient died in June 2000. The whole follow-up period was 76 months. We thought this case to be worth for presentation because this unusual long survival, which was probably due to the aggressive complex anticancer treatment.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalLung Cancer
Volume36
Issue number3
DOIs
Publication statusPublished - 2002

Fingerprint

Desmoplastic Small Round Cell Tumor
Pleura
Drug Therapy
Desmin
X Ray Computed Tomography
Carcinoid Tumor
Vincristine
Vimentin
Ribs
Thoracotomy
Back Pain
Keratins
Doxorubicin
Cyclophosphamide
Neoplasms
Radiotherapy
Thorax
Neoplasm Metastasis
Lung
Survival

Keywords

  • Chemotherapy
  • Desmoplastic small round cell tumour
  • Pleura

ASJC Scopus subject areas

  • Oncology

Cite this

Desmoplastic small round cell tumour of the pleura : A case report with unusual follow-up. / Ostoros, G.; Orosz, Zsolt; Kovács, Gábor; Soltész, Ilona.

In: Lung Cancer, Vol. 36, No. 3, 2002, p. 333-336.

Research output: Contribution to journalArticle

Ostoros, G. ; Orosz, Zsolt ; Kovács, Gábor ; Soltész, Ilona. / Desmoplastic small round cell tumour of the pleura : A case report with unusual follow-up. In: Lung Cancer. 2002 ; Vol. 36, No. 3. pp. 333-336.
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