Csontmutéteknél alkalmazható antibiotikum- tartalmú hordozórendszerek tervezése

Translated title of the contribution: Designing antibiotic-containing carrier systems used in bone surgery

Laki Mónika, Hajdú Mária, Zahár Ákos, Sáska Zsófia, I. Klebovich, M. Szendrői, I. Antal

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The controlled release of antibiotics from bone can significantly reduce the prevalence of septic complication of revision operations. Consequently, the patiens could avoid further operations and the hospitals could save the cost of repeated operations, which has economic notability too. The conditions of the correct antibiotic therapy are the right indication, the use of the most appropriate antibiotic, the right dose and the adequate duration of the therapy. The spread of antibiotic resistance is particularly important in the case of long residence time in a hospital. In revision surgery, periprothetic infections are principally caused by Staphylococcus aureus and Staphylococcus epidermidis, but in most cases it is needed to reckon with multiresistance strains. In such cases, patients take antibiotics for weeks before the surgery to heal the inflammation, in order to remove the infected prothesis in time and implant the new one.

Original languageHungarian
Pages (from-to)108-115
Number of pages8
JournalActa Pharmaceutica Hungarica
Volume77
Issue number2
Publication statusPublished - 2007

Fingerprint

Anti-Bacterial Agents
Bone and Bones
Staphylococcus epidermidis
Microbial Drug Resistance
Reoperation
Staphylococcus aureus
Economics
Inflammation
Costs and Cost Analysis
Therapeutics
Infection

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Csontmutéteknél alkalmazható antibiotikum- tartalmú hordozórendszerek tervezése. / Mónika, Laki; Mária, Hajdú; Ákos, Zahár; Zsófia, Sáska; Klebovich, I.; Szendrői, M.; Antal, I.

In: Acta Pharmaceutica Hungarica, Vol. 77, No. 2, 2007, p. 108-115.

Research output: Contribution to journalArticle

Mónika, Laki ; Mária, Hajdú ; Ákos, Zahár ; Zsófia, Sáska ; Klebovich, I. ; Szendrői, M. ; Antal, I. / Csontmutéteknél alkalmazható antibiotikum- tartalmú hordozórendszerek tervezése. In: Acta Pharmaceutica Hungarica. 2007 ; Vol. 77, No. 2. pp. 108-115.
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