Designed nucleophilic attack based on molecular electrostatic potential

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We describe the computer-aided design of the steric preference in a nucleophilic attack on sterically unbiased carbonyl groups. To our knowledge, this is the first example for the successful application of the molecular electrostatic potential map to computer-assisted synthesis.

Original languageEnglish
Pages (from-to)9255-9258
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number49
DOIs
Publication statusPublished - Dec 5 1994

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Designed nucleophilic attack based on molecular electrostatic potential'. Together they form a unique fingerprint.

  • Cite this