Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1

Akos Kertesz, Balazs Takacs, Gyorgyi Varadi, G. Tóth, G. Sármay

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A cell membrane permeable phosphopeptide corresponding to the SHP-2 binding motif of Grb2-associated binder 1 (Gab1) interferes with the Gab1 adaptor-dependent functions and modulates B cell receptor-triggered intracellular signaling in B cell tumors.

Original languageEnglish
Title of host publicationAnnals of the New York Academy of Sciences
Pages437-444
Number of pages8
Volume1091
DOIs
Publication statusPublished - Dec 2006

Publication series

NameAnnals of the New York Academy of Sciences
Volume1091
ISSN (Print)00778923
ISSN (Electronic)17496632

Fingerprint

Phosphopeptides
Binders
B-Lymphocytes
Cells
Cell membranes
Tumors
Cell Membrane
Neoplasms

Keywords

  • Burkitt lymphoma
  • Gab1
  • Immunomodulation
  • Phosphopeptides

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Kertesz, A., Takacs, B., Varadi, G., Tóth, G., & Sármay, G. (2006). Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1. In Annals of the New York Academy of Sciences (Vol. 1091, pp. 437-444). (Annals of the New York Academy of Sciences; Vol. 1091). https://doi.org/10.1196/annals.1378.086

Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1. / Kertesz, Akos; Takacs, Balazs; Varadi, Gyorgyi; Tóth, G.; Sármay, G.

Annals of the New York Academy of Sciences. Vol. 1091 2006. p. 437-444 (Annals of the New York Academy of Sciences; Vol. 1091).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kertesz, A, Takacs, B, Varadi, G, Tóth, G & Sármay, G 2006, Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1. in Annals of the New York Academy of Sciences. vol. 1091, Annals of the New York Academy of Sciences, vol. 1091, pp. 437-444. https://doi.org/10.1196/annals.1378.086
Kertesz A, Takacs B, Varadi G, Tóth G, Sármay G. Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1. In Annals of the New York Academy of Sciences. Vol. 1091. 2006. p. 437-444. (Annals of the New York Academy of Sciences). https://doi.org/10.1196/annals.1378.086
Kertesz, Akos ; Takacs, Balazs ; Varadi, Gyorgyi ; Tóth, G. ; Sármay, G. / Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1. Annals of the New York Academy of Sciences. Vol. 1091 2006. pp. 437-444 (Annals of the New York Academy of Sciences).
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