Description and plasmid characterization of qnrD determinants in Proteus mirabilis and Morganella morganii

A. Mazzariol, B. Kocsis, R. Koncan, E. Kocsis, P. Lanzafame, G. Cornaglia

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24 Citations (Scopus)

Abstract

We investigated the presence of qnrC and qnrD among 756 non-replicate Enterobacteriaceae isolated in Italy, selected for being non-susceptible to fluoroquinolones and/or resistant to third-generation cephalosporins. Four Proteus mirabilis and one Morganella morganii (0.66% of the total) presented a qnrD gene, located in a 2687-base-pair plasmid that was entirely sequenced. The plasmid is un-typable, and contains no known coding region other than qnrD. That the qnrD gene was found in four unrelated P. mirabilis and in one M. morganii isolate might suggest a frequent association of this gene with the tribe Proteeae.

Original languageEnglish
Pages (from-to)E46-E48
JournalClinical Microbiology and Infection
Volume18
Issue number3
DOIs
Publication statusPublished - Mar 2012

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Keywords

  • Fluoroquinolone resistance
  • Morganella morganii
  • Plasmid-mediated fluoroquinolone-resistance determinants
  • Proteus mirabilis
  • qnrD

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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