Description and interpretation of functional changes in canine kidneys after preservation with hypothermic perfusates and subsequent reperfusion

E. Rőth, T. Szmolenszky, B. Török

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The function of canine kidneys stored with hypothermic solutions (Rheomacrodex, Collins4, Sacks) was studied in acute autologous reperfusion models. Changes in the perfusates (increase in LDH level and minor increase in K+ level), as well as the quantitative and qualitative properties (proteinuria) of the urine produced by the graft may be ascribed to storage and revascularization which affect the cells and their membranes. The alterations of the circulatory parameters demonstrable at the outset and during revascularization are due to an increase in renovascular resistance of hypothermic origin on the one hand, and to acute tubular epithelial damage inherent in the procedure, on the other.

Original languageEnglish
Pages (from-to)335-347
Number of pages13
JournalInternational Urology and Nephrology
Volume10
Issue number4
DOIs
Publication statusPublished - Dec 1978

Fingerprint

Dextrans
Proteinuria
Reperfusion
Canidae
Cell Membrane
Urine
Transplants
Kidney

ASJC Scopus subject areas

  • Urology
  • Nephrology
  • Geriatrics and Gerontology

Cite this

Description and interpretation of functional changes in canine kidneys after preservation with hypothermic perfusates and subsequent reperfusion. / Rőth, E.; Szmolenszky, T.; Török, B.

In: International Urology and Nephrology, Vol. 10, No. 4, 12.1978, p. 335-347.

Research output: Contribution to journalArticle

@article{b72c80270ff047888596bc4a77c40ca3,
title = "Description and interpretation of functional changes in canine kidneys after preservation with hypothermic perfusates and subsequent reperfusion",
abstract = "The function of canine kidneys stored with hypothermic solutions (Rheomacrodex, Collins4, Sacks) was studied in acute autologous reperfusion models. Changes in the perfusates (increase in LDH level and minor increase in K+ level), as well as the quantitative and qualitative properties (proteinuria) of the urine produced by the graft may be ascribed to storage and revascularization which affect the cells and their membranes. The alterations of the circulatory parameters demonstrable at the outset and during revascularization are due to an increase in renovascular resistance of hypothermic origin on the one hand, and to acute tubular epithelial damage inherent in the procedure, on the other.",
author = "E. Rőth and T. Szmolenszky and B. T{\"o}r{\"o}k",
year = "1978",
month = "12",
doi = "10.1007/BF02082373",
language = "English",
volume = "10",
pages = "335--347",
journal = "International Urology and Nephrology",
issn = "0301-1623",
publisher = "Springer Netherlands",
number = "4",

}

TY - JOUR

T1 - Description and interpretation of functional changes in canine kidneys after preservation with hypothermic perfusates and subsequent reperfusion

AU - Rőth, E.

AU - Szmolenszky, T.

AU - Török, B.

PY - 1978/12

Y1 - 1978/12

N2 - The function of canine kidneys stored with hypothermic solutions (Rheomacrodex, Collins4, Sacks) was studied in acute autologous reperfusion models. Changes in the perfusates (increase in LDH level and minor increase in K+ level), as well as the quantitative and qualitative properties (proteinuria) of the urine produced by the graft may be ascribed to storage and revascularization which affect the cells and their membranes. The alterations of the circulatory parameters demonstrable at the outset and during revascularization are due to an increase in renovascular resistance of hypothermic origin on the one hand, and to acute tubular epithelial damage inherent in the procedure, on the other.

AB - The function of canine kidneys stored with hypothermic solutions (Rheomacrodex, Collins4, Sacks) was studied in acute autologous reperfusion models. Changes in the perfusates (increase in LDH level and minor increase in K+ level), as well as the quantitative and qualitative properties (proteinuria) of the urine produced by the graft may be ascribed to storage and revascularization which affect the cells and their membranes. The alterations of the circulatory parameters demonstrable at the outset and during revascularization are due to an increase in renovascular resistance of hypothermic origin on the one hand, and to acute tubular epithelial damage inherent in the procedure, on the other.

UR - http://www.scopus.com/inward/record.url?scp=0018160977&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018160977&partnerID=8YFLogxK

U2 - 10.1007/BF02082373

DO - 10.1007/BF02082373

M3 - Article

C2 - 365824

AN - SCOPUS:0018160977

VL - 10

SP - 335

EP - 347

JO - International Urology and Nephrology

JF - International Urology and Nephrology

SN - 0301-1623

IS - 4

ER -