Depressive disorders in patients with chronic kidney disease

Dora M. Zalai, Marta Novak

Research output: Contribution to journalReview article

5 Citations (Scopus)


Depressive disorders have been shown to be present in 20% to 40% of the population receiving renal-replacement therapy, and this figure may be even higher in the pre-dialysis chronic kidney disease (CKD) population. Psychosocial factors (eg, unemployment, low income, young age, female gender, low-perceived social support, lack of adjustment to the hardship of dialysis, role transitions) make patients vulnerable to depression. Although it is often impossible to tell whether some symptoms originate primary in CKD or depressive disorders, if they meet the diagnostic criteria of depressive disorders then adequate therapy should be initiated. Screening tools can help in the identification of patients with depressive disorders. Prevention and treatment of depression is crucial because it is strongly associated with several important CKD outcomes. Monitoring the presence of depressive symptoms and enhancing social support should be part of the routine care in the CKD population.

Original languageEnglish
Pages (from-to)66-72
Number of pages7
JournalPrimary Psychiatry
Issue number1
Publication statusPublished - Jan 1 2008

ASJC Scopus subject areas

  • Psychiatry and Mental health

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