Depressed monocyte production of interleukin‐1 and tumor necrosis factor‐alpha in patients with alcoholic liver cirrhosis

GY Müzes, GY Deák, I. Láng, R. González‐Cabello, P. Gergely, J. Fehér

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

ABSTRACT— Interleukin‐1 and tumor necrosis factor‐alpha activity by E. coli lipopolysaccharide‐triggered monocytes were studied in patients with chronic alcoholic liver disease. Monocytes from cirrhotic patients were shown to have a significant reduction in IL‐1 and TNF‐a activity, compared with that from age‐ and sex‐matched healthy controls. These findings indicate further immunoregulatory disturbances concerning alcoholic liver cirrhosis.

Original languageEnglish
Pages (from-to)302-306
Number of pages5
JournalLiver
Volume9
Issue number5
DOIs
Publication statusPublished - Oct 1989

Keywords

  • alcoholic liver cirrhosis
  • interleukin‐1
  • tumor necrosis factor‐alpha

ASJC Scopus subject areas

  • Hepatology

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