Dendritic spiking accounts for rate and phase coding in a biophysical model of a hippocampal place cell

Zsófia Huhn, Máté Lengyel, Gergo Orbán, P. Érdi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Hippocampal place cells provide prototypical examples of neurons jointly firing phase and rate-coded spike trains. We propose a biophysical mechanism accounting for the generation of place cell firing at the single neuron level. An interplay between external theta-modulated excitation impinging the dendrite and intrinsic dendritic spiking as well as between frequency-modulated dendritic spiking and somatic membrane potential oscillations was a key element of the model. Through these interactions robust phase and rate-coded firing emerged in the model place cell, reproducing salient experimentally observed properties of place cell firing.

Original languageEnglish
Pages (from-to)331-341
Number of pages11
JournalNeurocomputing
Volume65-66
Issue numberSPEC. ISS.
DOIs
Publication statusPublished - Jun 2005

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Neurons
Membranes
Dendrites
Membrane Potentials
Place Cells

Keywords

  • Active dendrite
  • Phase precession
  • Tuning curve

ASJC Scopus subject areas

  • Artificial Intelligence
  • Cellular and Molecular Neuroscience

Cite this

Dendritic spiking accounts for rate and phase coding in a biophysical model of a hippocampal place cell. / Huhn, Zsófia; Lengyel, Máté; Orbán, Gergo; Érdi, P.

In: Neurocomputing, Vol. 65-66, No. SPEC. ISS., 06.2005, p. 331-341.

Research output: Contribution to journalArticle

Huhn, Zsófia ; Lengyel, Máté ; Orbán, Gergo ; Érdi, P. / Dendritic spiking accounts for rate and phase coding in a biophysical model of a hippocampal place cell. In: Neurocomputing. 2005 ; Vol. 65-66, No. SPEC. ISS. pp. 331-341.
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