Dendritic spiking accounts for rate and phase coding in a biophysical model of a hippocampal place cell

Zsófia Huhn, Máté Lengyel, Gergo Orbán, Peter Érdi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Hippocampal place cells provide prototypical examples of neurons jointly firing phase and rate-coded spike trains. We propose a biophysical mechanism accounting for the generation of place cell firing at the single neuron level. An interplay between external theta-modulated excitation impinging the dendrite and intrinsic dendritic spiking as well as between frequency-modulated dendritic spiking and somatic membrane potential oscillations was a key element of the model. Through these interactions robust phase and rate-coded firing emerged in the model place cell, reproducing salient experimentally observed properties of place cell firing.

Original languageEnglish
Pages (from-to)331-341
Number of pages11
JournalNeurocomputing
Volume65-66
Issue numberSPEC. ISS.
DOIs
Publication statusPublished - Jun 1 2005

Keywords

  • Active dendrite
  • Phase precession
  • Tuning curve

ASJC Scopus subject areas

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence

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