Demonstration of the difference in binding affinity between the two binding sites of the ristocetin A asymmetric dimer

Gyula Batta, Michael F. Cristofaro, Gary J. Sharman, Dudley H. Williams

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The titration of 13C labelled N-acetyl-D-ala-D-ala with the glycopeptide antibiotics ristocetin A and eremomycin, monitored by 13C NMR spectroscopy, demonstrates that the two distinct binding sites of the ristocetin A asymmetric dimer have different affinities, whereas those of eremomycin show no detectable difference.

Original languageEnglish
Pages (from-to)101-103
Number of pages3
JournalChemical Communications
Issue number1
DOIs
Publication statusPublished - Jan 7 1996

    Fingerprint

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this