Deliveries from embryos fertilized with spermatozoa obtained from cryopreserved testicular tissue

Janos Konc, Katalin Kanyó, S. Cseh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Aim: The data of 167 TESE-ICSI-ET cycles performed with fresh or frozen, motile or immotile testicular spermatozoa were analyzed, retrospectively. Methods: The outcome measures studied were state/condition of spermatozoa, fertilization, embryo developmental, implantation and pregnancy/delivery and abortion rates. Results: No differences were found in fertilization, implantation and pregnancy rates of oocytes injected with fresh or frozen spermatozoa. However, difference was obtained in the fertilization rate of oocytes injected with motile vs. non-motile spermatozoa (72% vs. 62%; P <0.04). Difference was also observed in embryo development between oocytes injected with fresh vs. frozen spermatozoa (83% vs. 75%; P <0.03). But, no difference was obtained in embryo development between oocytes injected with motile vs. immotile spermatozoa. No difference was also found in the implantation rate of embryos developed from oocytes injected with motile vs. non-motile spermatozoa. No difference was found in abortion rates either. Conclusions: State/condition of injected testicular spermatozoa has impact to fertilization and embryo development. Pregnancy/delivery can be achieved with frozen/immotile spermatozoa.

Original languageEnglish
Pages (from-to)247-252
Number of pages6
JournalJournal of Assisted Reproduction and Genetics
Volume23
Issue number5
DOIs
Publication statusPublished - May 2006

Fingerprint

Spermatozoa
Embryonic Structures
Oocytes
Fertilization
Embryonic Development
Induced Abortion
Pregnancy Rate
Intracytoplasmic Sperm Injections
Outcome Assessment (Health Care)
Pregnancy

Keywords

  • Cryopreserved testicular tissue/spermatozoa
  • Embryo development
  • Embryo transfer (ET)
  • In vitro fertilization (IVF)
  • Intra cytoplasmic sperm injection (ICSI)
  • State/condition of spermatozoa
  • Testicular sperm extraction (TESE)

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Developmental Biology
  • Genetics
  • Reproductive Medicine

Cite this

Deliveries from embryos fertilized with spermatozoa obtained from cryopreserved testicular tissue. / Konc, Janos; Kanyó, Katalin; Cseh, S.

In: Journal of Assisted Reproduction and Genetics, Vol. 23, No. 5, 05.2006, p. 247-252.

Research output: Contribution to journalArticle

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