Delayed protection of the heart against ischaemia

J. R. Parratt, L. Szekeres

Research output: Contribution to journalReview article

60 Citations (Scopus)


Ischaemic preconditioning is the protective adaptive mechanism produced by short periods of ischaemic stress that results in a marked resistance of the myocardium to prolonged periods of the same stress; however, this protection is transient. There is now evidence that protection resulting from preconditioning returns several hours later, and here James Parratt and Laszlo Szekeres highlight the possible importance of this concept, which may lead to novel approaches to the long-term protection of the heart against ischaemic injury.

Original languageEnglish
Pages (from-to)351-355
Number of pages5
JournalTrends in Pharmacological Sciences
Issue number10
Publication statusPublished - Oct 1995


ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

Cite this