Four materials of different properties in respect of compressibility, lactose, sodium chloride, microcrystalline cellulose (Avicel PH 101) and so-called simple granulate were investigated. In function of time and that of actual pressing force decrease of axial force on upper punch were measured in quasi-state. Evaluating relations it was established that both pressing time and pressing force had influence on deformation structural changes occurring inside compressed form. Furthermore, summing up of results showed that useful conclusions could be drawn from diagrams--which represented decrease of force--to compressibility properties of materials too.
|Translated title of the contribution||Deformation phenomena occurring during compression. III. Changes of maximal compression strength in quasi-static condition|
|Number of pages||9|
|Journal||Acta pharmaceutica Hungarica|
|Publication status||Published - Jul 1 1990|
ASJC Scopus subject areas
- Pharmaceutical Science