Definition of Drosophila hemocyte subsets by cell-type specific antigens

E. Kurucz, B. Váczi, R. Márkus, Barbara Laurinyecz, P. Vilmos, J. Zsámboki, Kinga Csorba, Elisabeth Gateff, D. Hultmark, I. Andó

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes.

Original languageEnglish
Pages (from-to)95-111
Number of pages17
JournalActa Biologica Hungarica
Volume58
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Nov 2007

Fingerprint

Hemocytes
antigen
hemocytes
Drosophila
antigens
Antigens
Cells
Blood
blood
cells
Tissue
blood cells
Blood Cells
lymph
Lymph
crystal
Crystals
crystals
Chemical analysis
Population

Keywords

  • Drosophila
  • Hemocyte antigen
  • Hemocyte development
  • Hemocyte subpopulation
  • Monoclonal antibody

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Definition of Drosophila hemocyte subsets by cell-type specific antigens. / Kurucz, E.; Váczi, B.; Márkus, R.; Laurinyecz, Barbara; Vilmos, P.; Zsámboki, J.; Csorba, Kinga; Gateff, Elisabeth; Hultmark, D.; Andó, I.

In: Acta Biologica Hungarica, Vol. 58, No. SUPPL. 1, 11.2007, p. 95-111.

Research output: Contribution to journalArticle

Kurucz, E, Váczi, B, Márkus, R, Laurinyecz, B, Vilmos, P, Zsámboki, J, Csorba, K, Gateff, E, Hultmark, D & Andó, I 2007, 'Definition of Drosophila hemocyte subsets by cell-type specific antigens', Acta Biologica Hungarica, vol. 58, no. SUPPL. 1, pp. 95-111. https://doi.org/10.1556/ABiol.58.2007.Suppl.8
Kurucz, E. ; Váczi, B. ; Márkus, R. ; Laurinyecz, Barbara ; Vilmos, P. ; Zsámboki, J. ; Csorba, Kinga ; Gateff, Elisabeth ; Hultmark, D. ; Andó, I. / Definition of Drosophila hemocyte subsets by cell-type specific antigens. In: Acta Biologica Hungarica. 2007 ; Vol. 58, No. SUPPL. 1. pp. 95-111.
@article{975398798d3c4f5ea65faa98e39a0ac2,
title = "Definition of Drosophila hemocyte subsets by cell-type specific antigens",
abstract = "We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes.",
keywords = "Drosophila, Hemocyte antigen, Hemocyte development, Hemocyte subpopulation, Monoclonal antibody",
author = "E. Kurucz and B. V{\'a}czi and R. M{\'a}rkus and Barbara Laurinyecz and P. Vilmos and J. Zs{\'a}mboki and Kinga Csorba and Elisabeth Gateff and D. Hultmark and I. And{\'o}",
year = "2007",
month = "11",
doi = "10.1556/ABiol.58.2007.Suppl.8",
language = "English",
volume = "58",
pages = "95--111",
journal = "Acta Biologica Hungarica",
issn = "0236-5383",
publisher = "Akademiai Kiado",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Definition of Drosophila hemocyte subsets by cell-type specific antigens

AU - Kurucz, E.

AU - Váczi, B.

AU - Márkus, R.

AU - Laurinyecz, Barbara

AU - Vilmos, P.

AU - Zsámboki, J.

AU - Csorba, Kinga

AU - Gateff, Elisabeth

AU - Hultmark, D.

AU - Andó, I.

PY - 2007/11

Y1 - 2007/11

N2 - We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes.

AB - We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes.

KW - Drosophila

KW - Hemocyte antigen

KW - Hemocyte development

KW - Hemocyte subpopulation

KW - Monoclonal antibody

UR - http://www.scopus.com/inward/record.url?scp=38749148054&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38749148054&partnerID=8YFLogxK

U2 - 10.1556/ABiol.58.2007.Suppl.8

DO - 10.1556/ABiol.58.2007.Suppl.8

M3 - Article

VL - 58

SP - 95

EP - 111

JO - Acta Biologica Hungarica

JF - Acta Biologica Hungarica

SN - 0236-5383

IS - SUPPL. 1

ER -