Defects in innate immunity: Receptors and signaling components

M. Erdős, L. Máródi, Seyed Alireza Mahdaviani, Sergio D. Rosenzweig, Joachim Roesler, Nima Rezaei

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The innate immune system is the first-line host defense against microbial pathogens and is mediated by pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and nucleotide-binding and oligomerization domain (NOD)-like receptors (NLR). PRPs consist of secreted and circulating proteins, and intracellular and transmembrane signal-transducing components [1]. They recognize pathogen-associated molecular patterns (PAMPs).

Original languageEnglish
Title of host publicationClinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach
PublisherSpringer Berlin Heidelberg
Pages279-307
Number of pages29
ISBN (Print)9783642317859, 9783642317842
DOIs
Publication statusPublished - Jan 1 2012

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Pattern Recognition Receptors
Toll-Like Receptors
Innate Immunity
Immune System
Nucleotides
Proteins
Pathogen-Associated Molecular Pattern Molecules

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Erdős, M., Máródi, L., Mahdaviani, S. A., Rosenzweig, S. D., Roesler, J., & Rezaei, N. (2012). Defects in innate immunity: Receptors and signaling components. In Clinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach (pp. 279-307). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-31785-9_6

Defects in innate immunity : Receptors and signaling components. / Erdős, M.; Máródi, L.; Mahdaviani, Seyed Alireza; Rosenzweig, Sergio D.; Roesler, Joachim; Rezaei, Nima.

Clinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach. Springer Berlin Heidelberg, 2012. p. 279-307.

Research output: Chapter in Book/Report/Conference proceedingChapter

Erdős, M, Máródi, L, Mahdaviani, SA, Rosenzweig, SD, Roesler, J & Rezaei, N 2012, Defects in innate immunity: Receptors and signaling components. in Clinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach. Springer Berlin Heidelberg, pp. 279-307. https://doi.org/10.1007/978-3-642-31785-9_6
Erdős M, Máródi L, Mahdaviani SA, Rosenzweig SD, Roesler J, Rezaei N. Defects in innate immunity: Receptors and signaling components. In Clinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach. Springer Berlin Heidelberg. 2012. p. 279-307 https://doi.org/10.1007/978-3-642-31785-9_6
Erdős, M. ; Máródi, L. ; Mahdaviani, Seyed Alireza ; Rosenzweig, Sergio D. ; Roesler, Joachim ; Rezaei, Nima. / Defects in innate immunity : Receptors and signaling components. Clinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach. Springer Berlin Heidelberg, 2012. pp. 279-307
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