The innate immune system is the first-line host defense against microbial pathogens and is mediated by pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and nucleotide-binding and oligomerization domain (NOD)-like receptors (NLR). PRPs consist of secreted and circulating proteins, and intracellular and transmembrane signal-transducing components . They recognize pathogen-associated molecular patterns (PAMPs).
|Title of host publication||Clinical Cases in Primary Immunodeficiency Diseases|
|Subtitle of host publication||A Problem-Solving Approach|
|Publisher||Springer Berlin Heidelberg|
|Number of pages||29|
|Publication status||Published - Jan 1 2012|
ASJC Scopus subject areas
- Immunology and Microbiology(all)