Deep-probe metal-clad waveguide biosensors

N. Skivesen, R. Horváth, S. Thinggaard, N. B. Larsen, H. C. Pedersen

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150-200 nm. The dip-type metal-clad waveguide sensor is shown to be the best all-round alternative to the surface-plasmon resonance biosensor. Both metal-clad waveguides are tested experimentally for cell detection, showing a detection limit of 8-9 cells/mm2.

Original languageEnglish
Pages (from-to)1282-1288
Number of pages7
JournalBiosensors and Bioelectronics
Volume22
Issue number7
DOIs
Publication statusPublished - Feb 15 2007

Fingerprint

Clad metals
Biosensing Techniques
Biosensors
Waveguides
Surface Plasmon Resonance
Metals
Surface plasmon resonance
Limit of Detection
Sensors

Keywords

  • Biosensors
  • Cell detection
  • Refractometry
  • Waveguide sensors

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Electrochemistry

Cite this

Skivesen, N., Horváth, R., Thinggaard, S., Larsen, N. B., & Pedersen, H. C. (2007). Deep-probe metal-clad waveguide biosensors. Biosensors and Bioelectronics, 22(7), 1282-1288. https://doi.org/10.1016/j.bios.2006.05.025

Deep-probe metal-clad waveguide biosensors. / Skivesen, N.; Horváth, R.; Thinggaard, S.; Larsen, N. B.; Pedersen, H. C.

In: Biosensors and Bioelectronics, Vol. 22, No. 7, 15.02.2007, p. 1282-1288.

Research output: Contribution to journalArticle

Skivesen, N, Horváth, R, Thinggaard, S, Larsen, NB & Pedersen, HC 2007, 'Deep-probe metal-clad waveguide biosensors', Biosensors and Bioelectronics, vol. 22, no. 7, pp. 1282-1288. https://doi.org/10.1016/j.bios.2006.05.025
Skivesen, N. ; Horváth, R. ; Thinggaard, S. ; Larsen, N. B. ; Pedersen, H. C. / Deep-probe metal-clad waveguide biosensors. In: Biosensors and Bioelectronics. 2007 ; Vol. 22, No. 7. pp. 1282-1288.
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